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The PEG backbone enhances solubility and steric stability, while the thiol group enables strong covalent bonding to metallic surfaces, proteins, and polymers.\u003c\/p\u003e\n\n\u003cp\u003eApplications:\n\u003cbr\u003eSurface Modification: Forms self-assembled monolayers (SAMs) on gold, silver, and other metal surfaces, improving biointerface properties.\n\u003cbr\u003eBioconjugation \u0026amp; Drug Delivery: Reacts with maleimide-functionalized molecules for targeted nanoparticle and drug carrier functionalization.\n\u003cbr\u003eHydrogel Crosslinking: Enables thiol-based crosslinking in biodegradable hydrogel networks for controlled drug release and tissue scaffolds.\n\u003cbr\u003eElectrochemical Sensors: Enhances stability and antifouling properties in biosensors and medical diagnostic platforms.\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"26059-1 (1 g)","offer_id":46425788285142,"sku":"26059-1","price":566.5,"currency_code":"USD","in_stock":true},{"title":"26059-5 (5 g)","offer_id":46425788317910,"sku":"26059-5","price":950.18,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/logo_only-431927_143bc587-078c-4eb4-9fde-3c425e047e87-474194.jpg?v=1738078477"},{"product_id":"peg-methyl-ether-thiol-mp-2000","title":"PEG methyl ether thiol, Mp 2000","description":"\u003c!-- PDP Content: 26060-1 — PEG methyl ether thiol, Mp 2000 (mPEG-SH) --\u003e\n\u003csection class=\"pdp-content\" aria-label=\"Product information\"\u003e\n\n  \u003cstyle\u003e\n    \/* ===== Ultra-tight layout (matches your latest adjusted products) ===== *\/\n    .pdp-content { line-height: 1.5; }\n\n    .pdp-content h2 {\n      font-size: 1.3rem;\n      font-weight: 700;\n      margin: 0.8rem 0 0.25rem;\n    }\n\n    .pdp-content h3 {\n      font-size: 1.05rem;\n      font-weight: 700;\n      margin: 0.6rem 0 0.2rem;\n    }\n\n    .pdp-content p { margin: 0 0 0.35rem; }\n\n    .pdp-content ul {\n      margin: 0.25rem 0 0.4rem;\n      padding-left: 1.05rem;\n    }\n\n    .pdp-content li { margin: 0.2rem 0; }\n\n    \/* Divider – very tight *\/\n    .pdp-divider {\n      border: 0;\n      border-top: 1px solid rgba(0,0,0,0.15);\n      margin: 0.45rem 0 0.35rem;\n    }\n\n    .pdp-divider + h3,\n    .pdp-divider + h2 { margin-top: 0; }\n\n    \/* ===== FAQ Section (same hierarchy + bullet expand pattern) ===== *\/\n    .pdp-faq h2 {\n      font-size: 1.3rem;\n      font-weight: 700;\n      margin: 0 0 0.25rem;\n    }\n\n    .pdp-faq .faq-intro {\n      margin: 0 0 0.4rem;\n      line-height: 1.45;\n      color: #333;\n    }\n\n    .pdp-faq ul {\n      margin: 0;\n      padding-left: 1.05rem;\n      list-style: disc;\n    }\n\n    .pdp-faq li { margin-bottom: 0.4rem; }\n\n    .pdp-faq summary {\n      cursor: pointer;\n      font-weight: 600;\n      line-height: 1.35;\n      list-style: none;\n      display: list-item;\n      -webkit-tap-highlight-color: transparent;\n    }\n\n    .pdp-faq summary::-webkit-details-marker { display: none; }\n\n    .pdp-faq details[open] summary { margin-bottom: 0.15rem; }\n\n    .pdp-faq .answer {\n      margin-left: 1rem;\n      line-height: 1.5;\n      font-size: 0.95rem;\n    }\n\n    .pdp-faq .answer p { margin: 0.2rem 0 0.35rem; }\n\n    @media (max-width: 480px) {\n      .pdp-content h2,\n      .pdp-faq h2 { font-size: 1.2rem; }\n      .pdp-faq .answer { margin-left: 0.85rem; }\n    }\n  \u003c\/style\u003e\n\n  \u003c!-- Title --\u003e\n  \u003ch2\u003ePEG methyl ether thiol (mPEG-SH), Mp 2000\u003c\/h2\u003e\n\n  \u003c!-- Quick identifier --\u003e\n  \u003cp\u003eThiol-functionalized polyethylene glycol\u003c\/p\u003e\n\n  \u003c!-- Product Description --\u003e\n  \u003chr class=\"pdp-divider\"\u003e\n  \u003ch3\u003eProduct Description\u003c\/h3\u003e\n  \u003cp\u003e\n    PEG Methyl Ether Thiol (mPEG-SH) is a thiol (–SH)–functionalized polyethylene glycol designed for surface\n    modification, polymer functionalization, and bioconjugation research. The polymer consists of a hydrophilic PEG\n    backbone terminated with a reactive thiol end group, enabling site-specific chemical coupling and surface attachment.\n  \u003c\/p\u003e\n  \u003cp\u003e\n    The PEG backbone provides aqueous solubility and steric stabilization, while the terminal thiol group supports\n    covalent coupling through thiol-based chemistries, including thiol–ene and thiol–maleimide reactions. These\n    properties make mPEG-SH a commonly used building block for modifying metals, polymers, and biomolecules, as well as\n    for developing redox-responsive and crosslinked polymer systems.\n  \u003c\/p\u003e\n  \u003cp\u003e\n    Due to its combination of reactivity, solubility, and biocompatibility, mPEG-SH is utilized in materials science,\n    biomedical research, and sensor development.\n  \u003c\/p\u003e\n\n  \u003c!-- Key Properties --\u003e\n  \u003chr class=\"pdp-divider\"\u003e\n  \u003ch3\u003eKey Properties\u003c\/h3\u003e\n  \u003cul\u003e\n    \u003cli\u003e\n\u003cstrong\u003ePolymer type:\u003c\/strong\u003e Polyethylene glycol, methyl ether thiol-terminated\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eFunctional group:\u003c\/strong\u003e Thiol (–SH)\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eBackbone:\u003c\/strong\u003e PEG (hydrophilic, non-ionic)\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eReactivity:\u003c\/strong\u003e Compatible with thiol–ene and thiol–maleimide chemistries\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eSolubility:\u003c\/strong\u003e Readily soluble in water and many polar organic solvents\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eStabilization:\u003c\/strong\u003e Provides steric stabilization and surface passivation\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003c!-- Typical Applications --\u003e\n  \u003chr class=\"pdp-divider\"\u003e\n  \u003ch3\u003eTypical Applications\u003c\/h3\u003e\n  \u003cp\u003e\n    PEG Methyl Ether Thiol (mPEG-SH) is commonly used in research and development applications requiring controlled\n    surface chemistry and polymer functionalization, including:\n  \u003c\/p\u003e\n  \u003cul\u003e\n    \u003cli\u003e\n      \u003cstrong\u003eSurface modification\u003c\/strong\u003e\u003cbr\u003e\n      Formation of self-assembled monolayers (SAMs) on gold, silver, and other metal surfaces to modify interfacial and\n      biointerface properties\n    \u003c\/li\u003e\n    \u003cli\u003e\n      \u003cstrong\u003eBioconjugation and drug delivery research\u003c\/strong\u003e\u003cbr\u003e\n      Conjugation with maleimide-functionalized molecules for nanoparticle, polymer, and carrier surface modification\n    \u003c\/li\u003e\n    \u003cli\u003e\n      \u003cstrong\u003eHydrogel crosslinking\u003c\/strong\u003e\u003cbr\u003e\n      Thiol-based crosslinking in hydrogel networks for controlled release and scaffold research\n    \u003c\/li\u003e\n    \u003cli\u003e\n      \u003cstrong\u003eElectrochemical and biosensor development\u003c\/strong\u003e\u003cbr\u003e\n      Surface passivation and antifouling modification in sensor and diagnostic research platforms\n    \u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003c!-- Synonyms \/ Acronyms --\u003e\n  \u003chr class=\"pdp-divider\"\u003e\n  \u003ch3\u003eSynonyms \/ Acronyms\u003c\/h3\u003e\n  \u003cul\u003e\n    \u003cli\u003emPEG-SH\u003c\/li\u003e\n    \u003cli\u003eThiol-terminated PEG\u003c\/li\u003e\n    \u003cli\u003ePEG methyl ether thiol\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003c!-- FAQs --\u003e\n  \u003csection class=\"pdp-faq\" aria-labelledby=\"pdp-faq-title\"\u003e\n    \u003chr class=\"pdp-divider\"\u003e\n\n    \u003ch2 id=\"pdp-faq-title\"\u003eFAQs\u003c\/h2\u003e\n    \u003cp class=\"faq-intro\"\u003eCommon questions about \u003cstrong\u003ePEG methyl ether thiol (mPEG-SH), Mp 2000\u003c\/strong\u003e.\u003c\/p\u003e\n\n    \u003cul\u003e\n      \u003cli\u003e\n        \u003cdetails\u003e\n          \u003csummary\u003eWhat is mPEG-SH used for?\u003c\/summary\u003e\n          \u003cdiv class=\"answer\"\u003e\n            \u003cp\u003e\n              mPEG-SH is commonly used for surface modification, polymer functionalization, and bioconjugation research\n              where a PEG chain with a reactive thiol end group is needed for site-specific coupling.\n            \u003c\/p\u003e\n          \u003c\/div\u003e\n        \u003c\/details\u003e\n      \u003c\/li\u003e\n\n      \u003cli\u003e\n        \u003cdetails\u003e\n          \u003csummary\u003eWhat does “thiol-terminated PEG” mean?\u003c\/summary\u003e\n          \u003cdiv class=\"answer\"\u003e\n            \u003cp\u003e\n              It indicates the PEG chain has a terminal thiol (–SH) functional group. The thiol provides a reactive handle\n              for thiol-based coupling chemistries and surface attachment strategies.\n            \u003c\/p\u003e\n          \u003c\/div\u003e\n        \u003c\/details\u003e\n      \u003c\/li\u003e\n\n      \u003cli\u003e\n        \u003cdetails\u003e\n          \u003csummary\u003eWhat reactions is mPEG-SH compatible with?\u003c\/summary\u003e\n          \u003cdiv class=\"answer\"\u003e\n            \u003cp\u003e\n              This material is commonly used in thiol-based chemistries, including thiol–ene and thiol–maleimide\n              reactions. Reaction suitability depends on the specific reagents and conditions used.\n            \u003c\/p\u003e\n          \u003c\/div\u003e\n        \u003c\/details\u003e\n      \u003c\/li\u003e\n\n      \u003cli\u003e\n        \u003cdetails\u003e\n          \u003csummary\u003eWhy is PEG used for surface passivation or antifouling studies?\u003c\/summary\u003e\n          \u003cdiv class=\"answer\"\u003e\n            \u003cp\u003e\n              PEG chains are widely studied for providing steric stabilization and reducing non-specific interactions at\n              interfaces. Outcomes depend on surface chemistry, PEG chain length, and experimental conditions.\n            \u003c\/p\u003e\n          \u003c\/div\u003e\n        \u003c\/details\u003e\n      \u003c\/li\u003e\n\n      \u003cli\u003e\n        \u003cdetails\u003e\n          \u003csummary\u003eWhat does Mp 2000 indicate?\u003c\/summary\u003e\n          \u003cdiv class=\"answer\"\u003e\n            \u003cp\u003e\n              Mp refers to an approximate molecular weight (or molecular weight peak designation) around 2,000 for the PEG\n              chain. Actual distribution and characterization method can influence reported values.\n            \u003c\/p\u003e\n          \u003c\/div\u003e\n        \u003c\/details\u003e\n      \u003c\/li\u003e\n    \u003c\/ul\u003e\n  \u003c\/section\u003e\n\n\u003c\/section\u003e\n","brand":"Polysciences","offers":[{"title":"26060-1 (1 g)","offer_id":46425788448982,"sku":"26060-1","price":430.54,"currency_code":"USD","in_stock":true},{"title":"26060-5 (5 g)","offer_id":46425788481750,"sku":"26060-5","price":931.73,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/NEW_methoxy__thiol___peg_methyl_ether_thiol__1_f1247390-96d7-4e1a-ba81-ac140ec82e7f.png?v=1738252723"},{"product_id":"peg-methyl-ether-thiol-mp-5000","title":"PEG methyl ether thiol, Mp 5000","description":"\u003cp\u003ePEG Methyl Ether Thiol (mPEG-SH) is a thiol (-SH) functionalized polyethylene glycol, commonly used for surface modification, thiol-ene click reactions, and redox-sensitive polymer applications. 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