{"title":"Polyethylenimine (PEI)","description":"\u003cp data-start=\"581\" data-end=\"1072\"\u003ePolyethylenimine (PEI) is a versatile cationic polymer widely used in transfection, gene delivery, surface coating, and nanoparticle synthesis. Polysciences offers a range of linear and branched PEI polymers in various molecular weights and purities to meet your research or formulation needs. Trusted by academic and industrial labs, our PEI products deliver high efficiency and consistency. Need help selecting the right grade? Our technical experts are here to assist.\u003c\/p\u003e","products":[{"product_id":"polyethylenimine-branched-mw-1800","title":"Polyethylenimine, Branched, Mw 2000 (bPEI 2000)","description":"\u003cp\u003eBranched polyethyleneimine (bPEI), MW ~1,800, is a highly branched polyamine with high cationic charge density. This water-soluble polymer contains primary, secondary, and tertiary amine groups that enable strong interaction with negatively charged surfaces and materials.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eSynonyms and related names:\u003c\/strong\u003e Branched PEI, bPEI, polyethyleneimine branched polymer, cationic polyethyleneimine, PEI polymer.\u003c\/p\u003e\n\n\u003cp\u003eBranched polyethyleneimine polymers are widely used in industrial and research applications because of their strong adsorption behavior, high amine functionality, and cationic charge density. PEI materials are commonly utilized in coatings, water treatment, adhesives, detergents, cosmetics, and paper processing applications.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eProduct specifications:\u003c\/strong\u003e Resin Content ≥99%; Cationic Charge Density: 16 meq\/g.\u003c\/p\u003e\n\n\u003ch2\u003eKey Properties\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eHighly branched polyamine polymer\u003c\/li\u003e\n\u003cli\u003eHigh cationic charge density\u003c\/li\u003e\n\u003cli\u003eWater-soluble polymer system\u003c\/li\u003e\n\u003cli\u003eContains primary, secondary, and tertiary amine groups\u003c\/li\u003e\n\u003cli\u003eStrong adsorption to negatively charged surfaces\u003c\/li\u003e\n\u003cli\u003eUseful in industrial and polymer processing applications\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\n\u003ch3\u003eWater Treatment\u003c\/h3\u003e\n\u003cp\u003eBranched polyethyleneimine is commonly used in water treatment processes where cationic polymers are needed for surface interaction and contaminant control.\u003c\/p\u003e\n\n\u003ch3\u003ePaper \u0026amp; Pulp Processing\u003c\/h3\u003e\n\u003cp\u003ebPEI polymers are widely utilized as auxiliary agents in papermaking and paper treatment applications.\u003c\/p\u003e\n\n\u003ch3\u003eAdhesives \u0026amp; Coatings\u003c\/h3\u003e\n\u003cp\u003eThe polymer’s high amine functionality and charge density support use in coatings, adhesives, and surface modification systems.\u003c\/p\u003e\n\n\u003ch3\u003eIndustrial Formulations\u003c\/h3\u003e\n\u003cp\u003ePolyethyleneimine materials are used in detergents, cosmetics, polymer formulations, and manufacturing workflows requiring cationic polymer functionality.\u003c\/p\u003e\n\n\u003ch2\u003eCompatibility \u0026amp; Solubility\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eWater-soluble branched polymer\u003c\/li\u003e\n\u003cli\u003eStrong interaction with negatively charged surfaces\u003c\/li\u003e\n\u003cli\u003eCompatible with many aqueous formulation systems\u003c\/li\u003e\n\u003cli\u003eUseful in cationic polymer processing applications\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eFinal formulation behavior depends on polymer concentration, pH, substrate composition, and processing conditions.\u003c\/p\u003e\n\n\u003ch2\u003ePreparation Tips\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eUse clean laboratory or processing equipment during formulation preparation\u003c\/li\u003e\n\u003cli\u003eAdd polymer gradually during mixing procedures\u003c\/li\u003e\n\u003cli\u003eOptimize concentration levels for target application performance\u003c\/li\u003e\n\u003cli\u003ePerform compatibility testing with new formulations\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eHandling \u0026amp; Storage\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eStore in a cool, dry environment\u003c\/li\u003e\n\u003cli\u003eKeep container tightly closed when not in use\u003c\/li\u003e\n\u003cli\u003eAvoid contamination during handling\u003c\/li\u003e\n\u003cli\u003eFollow standard laboratory and industrial handling procedures\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr class=\"pdp-divider\"\u003e\n\n\u003ch3\u003eWhy Choose Polysciences?\u003c\/h3\u003e\n\n\u003cdiv class=\"pdp-trust-signals\" style=\"display:grid;grid-template-columns:repeat(2,1fr);gap:14px;max-width:560px;margin:24px 0;\"\u003e\n  \n  \u003cdiv style=\"border:1px solid #17458f;border-radius:10px;padding:18px 14px;text-align:center;background:#fff;\"\u003e\n    \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/Research_Labs.png?v=1778099422\" alt=\"Research laboratories icon\" style=\"width:42px;height:42px;object-fit:contain;display:block;margin:0 auto 12px;\"\u003e\n    \u003cdiv style=\"font-family:inherit;font-size:14px;line-height:1.3;font-weight:700;color:#12386b;\"\u003e\n      Trusted by 6,000+ Researchers Worldwide\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\n  \u003cdiv style=\"border:1px solid #17458f;border-radius:10px;padding:18px 14px;text-align:center;background:#fff;\"\u003e\n    \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/Peer-Reviewed.png?v=1778099423\" alt=\"Peer reviewed studies icon\" style=\"width:42px;height:42px;object-fit:contain;display:block;margin:0 auto 12px;\"\u003e\n    \u003cdiv style=\"font-family:inherit;font-size:14px;line-height:1.3;font-weight:700;color:#12386b;\"\u003e\n      Cited in Thousands of Peer-Reviewed Studies\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\n  \u003cdiv style=\"border:1px solid #17458f;border-radius:10px;padding:18px 14px;text-align:center;background:#fff;\"\u003e\n    \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/USA.png?v=1778099422\" alt=\"Made in USA icon\" style=\"width:42px;height:42px;object-fit:contain;display:block;margin:0 auto 12px;\"\u003e\n    \u003cdiv style=\"font-family:inherit;font-size:14px;line-height:1.3;font-weight:700;color:#12386b;\"\u003e\n      U.S. Manufacturing \u0026amp; Global Distribution\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\n  \u003cdiv style=\"border:1px solid #17458f;border-radius:10px;padding:18px 14px;text-align:center;background:#fff;\"\u003e\n    \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/Delivery.png?v=1778099422\" alt=\"Global delivery icon\" style=\"width:42px;height:42px;object-fit:contain;display:block;margin:0 auto 12px;\"\u003e\n    \u003cdiv style=\"font-family:inherit;font-size:14px;line-height:1.3;font-weight:700;color:#12386b;\"\u003e\n      Reliable Delivery to 40+ Countries\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\n\u003c\/div\u003e\n\n\u003ch2\u003eFAQ\u003c\/h2\u003e\n\u003cp\u003eClick a question to expand.\u003c\/p\u003e\n\n\u003cdiv class=\"faq-accordion\"\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e1. What is branched polyethyleneimine used for?\u003c\/summary\u003e\n\u003cp\u003eBranched polyethyleneimine is used in water treatment, coatings, adhesives, paper processing, detergents, and industrial polymer applications.\u003c\/p\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e2. What does PEI stand for?\u003c\/summary\u003e\n\u003cp\u003ePEI stands for polyethyleneimine, a highly branched cationic polyamine polymer.\u003c\/p\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e3. Why is branched PEI highly cationic?\u003c\/summary\u003e\n\u003cp\u003eBranched PEI contains multiple primary, secondary, and tertiary amine groups that contribute to its high cationic charge density.\u003c\/p\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e4. Is branched polyethyleneimine water soluble?\u003c\/summary\u003e\n\u003cp\u003eYes. Branched polyethyleneimine is water soluble and compatible with many aqueous formulation systems.\u003c\/p\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e5. What types of surfaces interact with PEI polymers?\u003c\/summary\u003e\n\u003cp\u003ePEI polymers strongly adsorb onto negatively charged surfaces including cellulose, metals, polyesters, and polyamides.\u003c\/p\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003ch2\u003eSafety \u0026amp; Documentation\u003c\/h2\u003e\n\u003cp\u003eFollow standard laboratory and industrial safety procedures when handling cationic polymer materials. Refer to the product Safety Data Sheet (SDS) for complete handling, storage, and safety information.\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"06089-100 (100 g)","offer_id":46425687949526,"sku":"06089-100","price":76.0,"currency_code":"USD","in_stock":true},{"title":"06089-500 (500 g)","offer_id":46425687982294,"sku":"06089-500","price":176.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/basf_lupasol_pr8515_bpei_1800_cat_06089.png?v=1744041171"},{"product_id":"polyethylenimine-branched-mw-50000-100000","title":"Polyethylenimine, branched (30% soln. in water, MW 70,000)","description":"\u003cp\u003ePolyethylenimine (PEI) is a highly branched cationic polymer known for its strong ionic interactions, high charge density, and excellent adhesion properties. Its unique structure enables efficient complexation with nucleic acids, making it widely used in gene delivery, surface modifications, and flocculation applications. PEI’s ability to interact with negatively charged surfaces also enhances its role as a dispersant, emulsifier, and adhesion promoter. \n\u003cbr\u003ebPEI 70000 contains primary, secondary, and tertiary amine groups in approximately 25\/50\/25 ratio.\u003c\/p\u003e\n\n\u003cp\u003eApplications:\u003c\/p\u003e\n\n\u003cp\u003eGene Delivery \u0026amp; Biotechnology: Acts as a non-viral vector in DNA\/RNA transfection for gene therapy and biomedical research.\u003c\/p\u003e\n\n\u003cp\u003eCoatings \u0026amp; Adhesives: Enhances adhesion, water resistance, and crosslinking in industrial coatings, paints, and adhesives.\u003c\/p\u003e\n\n\u003cp\u003eWater Treatment \u0026amp; Flocculants: Functions as a cationic flocculant and dispersant for wastewater treatment and industrial processes.\u003c\/p\u003e\n\n\u003cp\u003ePaper \u0026amp; Textile Industry: Improves ink retention and surface properties in paper coatings and textile treatments.\u003c\/p\u003e\n\n\u003cp\u003eCatalyst \u0026amp; Resin Modification: Serves as a functional polymer in ion-exchange resins, catalyst supports, and crosslinked networks.\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"06090-100 (100 g)","offer_id":46425688015062,"sku":"06090-100","price":202.24,"currency_code":"USD","in_stock":true},{"title":"06090-25 (25 g)","offer_id":46425688047830,"sku":"06090-25","price":64.26,"currency_code":"USD","in_stock":true},{"title":"06090-500 (500 g)","offer_id":46425688080598,"sku":"06090-500","price":544.24,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/NEW_00618_2_2_1_4c4dbfd7-9631-4561-a66b-91d7aa28b0cd.png?v=1738253238"},{"product_id":"polyethylenimine-branched-30-soln-in-water-mw-10000","title":"Polyethylenimine, Branched, Mw 10,000, 30% w\/v aq. soln. (bPEI 10000 30% soln.)","description":"\u003cp\u003eBranched Polyethylenimine, Mw 10,000, 30 % w\/v aq. soln. (bPEI 10000 30% soln.) is highly branched polyamine with high cationic charge density. bPEI 10000 contains primary, secondary, and tertiary amine groups in approximately 25\/50\/25 ratio.Industrially, branched polyethylenimine (bPEI) have extensive applications as an auxiliary agent intensifying manufacturing processes and improving quality of the final products. They are widely used in: paper-making, water treatment, detergents, adhesives, and cosmetics. In research, they are extensively investigated as non-viral vector carriers.\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"17938-100 (100 g)","offer_id":46425712361686,"sku":"17938-100","price":201.16,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/polyethylenimine-branched_2_1_5e44674c-31ab-4c79-b8c4-a339387c478e.jpg?v=1735830388"},{"product_id":"polyethylenimine-branched-mw-70-000-50-w-v-aq-soln-bpei-70000-50-soln","title":"Polyethylenimine, Branched, Mw 70,000, 50% w\/v aq. soln. (bPEI 70000 50% soln.)","description":"\u003cp\u003ePolyethylenimine (PEI), branched, is a highly cationic, water-soluble polymer composed of primary, secondary, and tertiary amines. Its high charge density and strong nucleophilic properties make it an effective agent for adhesion, dispersion, and complex formation. PEI is widely used in industrial applications, including coatings, adhesives, flocculants, and surface modifications, where strong ionic interactions and crosslinking are required.\u003c\/p\u003e\n\n\u003cp\u003eApplications:\n\u003cbr\u003eAdhesives \u0026amp; Sealants: Acts as a crosslinking agent to enhance adhesion and mechanical strength in industrial formulations.\n\u003cbr\u003eCoatings \u0026amp; Surface Treatments: Modifies surfaces for improved wettability, charge control, and functionalization.\n\u003cbr\u003eFlocculants \u0026amp; Water Treatment: Facilitates particle aggregation and separation in wastewater treatment processes.\n\u003cbr\u003ePolymer Blends \u0026amp; Composites: Enhances dispersion and binding in composite materials for improved mechanical properties.\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"26292-1 (1 kg)","offer_id":46425816891606,"sku":"26292-1","price":344.43,"currency_code":"USD","in_stock":true},{"title":"26292-25 (25 g)","offer_id":46425816924374,"sku":"26292-25","price":50.74,"currency_code":"USD","in_stock":true},{"title":"26292-250 (250 g)","offer_id":46425816957142,"sku":"26292-250","price":137.45,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/polyethylenimine-branched_2_3_1_df7d8cda-9df2-4ce5-8c0c-e9a0121ecc1f.jpg?v=1736779675"},{"product_id":"polyethylenimine-branched-mw-600","title":"Polyethylenimine, Branched, Mw 600 (bPEI 600)","description":"\u003cp\u003eHighly branched polyamine with high charge density. Liquid polymers. Polymers contain primary, secondary, and tertiary amine groups in approximately 25\/50\/25 ratio.\n\u003cbr\u003eSee poly(2-ethyl-2-oxazoline) for precursors to linear polyethylenimine.\u003c\/p\u003e\n\n\u003cp\u003ePurity: 99%\n\u003cbr\u003ePolydispersity: 1.08\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"02371-100 (100 g)","offer_id":46437280579798,"sku":"02371-100","price":102.0,"currency_code":"USD","in_stock":true},{"title":"02371-500 (500 g)","offer_id":46437280612566,"sku":"02371-500","price":297.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/polyethylenimine-branched_a03cc7e4-dc2b-41ab-a3a6-95ed87509453-977630.jpg?v=1737983982"},{"product_id":"polyethylenimine-branched-mw-1200","title":"Polyethylenimine, Branched, Mw 1,200 (bPEI 1200)","description":"\u003cp\u003eBranched Polyethylenimine, Mw 1,200 (bPEI 1200) is highly branched liquid water soluble polyamine with high cationic charge density.\u003c\/p\u003e\n\n\u003cp\u003eIndustrially, branched polyethylenimine (bPEI) have extensive applications as an auxiliary agent intensifying manufacturing processes and improving quality of the final products. They are widely used in: paper-making, water treatment, detergents, adhesives, and cosmetics. In research, they are extensively investigated as non-viral vector carriers.\u003c\/p\u003e\n\n\u003cp\u003eResin Content (wt%): ≥99%\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"06088-25 (25 g)","offer_id":46437289558230,"sku":"06088-25","price":33.0,"currency_code":"USD","in_stock":true},{"title":"06088-100 (100 g)","offer_id":46437289590998,"sku":"06088-100","price":57.0,"currency_code":"USD","in_stock":true},{"title":"06088-500 (500 g)","offer_id":46437289623766,"sku":"06088-500","price":212.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/polyethylenimine-branched_1_6cfc89e8-a4b2-495a-a2a1-f63e5f3cedf4-375281.jpg?v=1737983868"},{"product_id":"polyethylenimine-linear-mw-250000","title":"Polyethylenimine, Linear, MW 250,000 (PEI 250000)","description":"\u003cp\u003eLinear polyethylenimine (PEI) is a high-charge cationic polymer that readily binds highly anionic substrates. Industrially, linear PEI can improve the appearance of negatively charged dyes by modulating their properties and improving their adherence to surfaces. In research, PEI readily binds to DNA and other negatively charged biological molecules, making it one of the most efficient vector carriers available.Product contains 7-11% of the acylated amine (N-propionyl) from isomerization-polymerization of 2-ethyl-2-oxazoline followed by acid-hydrolysis of resulting N-propionyl-PEI. Protein Expr Purif. 82(1):61-9.\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"24314-2 (2 g)","offer_id":46494454415574,"sku":"24314-2","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/kyfora_logo_6642bd9f-9bf4-4727-81bf-ecdd93505151.png?v=1738251970"},{"product_id":"polyethylenimine-linear-mw-100000","title":"Polyethylenimine, Linear, MW 100,000 (PEI 100000)","description":"\u003cp\u003eLinear polyethylenimine (PEI) is a high-charge cationic polymer that readily binds highly anionic substrates. Industrially, linear PEI can improve the appearance of negatively charged dyes by modulating their properties and improving their adherence to surfaces. In research, PEI readily binds to DNA and other negatively charged biological molecules, making it one of the most efficient vector carriers available.\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"25414-2 (2 g)","offer_id":46494454546646,"sku":"25414-2","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/kyfora_logo_80d1a450-e0e2-4455-8a7d-6ca65474a924.png?v=1738251970"},{"product_id":"polyethylenimine-branched-mw-10000","title":"Polyethylenimine, branched (MW 10,000)","description":"\u003cp\u003eHighly branched polyamine with high charge density. Liquid polymers.\n\u003cbr\u003ePolymers contain primary, secondary, and tertiary amine groups in approximately 25\/50\/25 ratio.\n\u003cbr\u003eSee poly(2-ethyl-2-oxazoline) for precursors to linear polyethylenimine.\u003c\/p\u003e\n\n\u003cp\u003ePurity: 99%\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"19850-100 (100 g)","offer_id":46494466736342,"sku":"19850-100","price":0.0,"currency_code":"USD","in_stock":true},{"title":"19850-500 (500 g)","offer_id":46494466769110,"sku":"19850-500","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/kyfora_logo_ead8a8c4-9749-455c-8143-bdbb7db60f01.png?v=1738251969"},{"product_id":"polyethylenimine-linear-mw-2-500-pei-2500","title":"Polyethylenimine, Linear, MW 2,500 (PEI 2500)","description":"\u003cp\u003e\u003cspan\u003eLinear polyethylenimine (L-PEI 2500) is a high-charge cationic polymer that readily binds highly anionic substrates. Industrially, linear PEI can improve the appearance of negatively charged dyes by modulating their properties and improving their adherence to surfaces.\u003c\/span\u003e\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"24313 (2 g)","offer_id":46495417172182,"sku":"24313","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/kyfora_logo_ead8a8c4-9749-455c-8143-bdbb7db60f01.png?v=1738251969"},{"product_id":"polyethylenimine-linear-mw-25000","title":"Polyethylenimine, Linear, MW 25000, Transfection Grade (PEI 25K™)","description":"\u003cdiv\u003e\n\u003cdiv class=\"description\"\u003e\n\u003cp\u003ePEI 25K is a powerful, trusted, and cost-effective transient transfection reagent. In HEK293 and CHO expression systems, PEI offers consistently high gene expression on a wide scale (96 well plates up to 100 L bioreactors). Each year, more researchers and companies turn to Polysciences PEI to gain a critical edge in their work. Relative to most other options, using PEI to prepare transfection reagents in-house can offer as much as a 40% reduction in total transfection costs.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Polysciences","offers":[{"title":"23966 (100) (100 mg)","offer_id":46536954446038,"sku":"23966 (100)","price":0.0,"currency_code":"USD","in_stock":true},{"title":"23966 (1) (1 g)","offer_id":46536955887830,"sku":"23966 (1)","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/pei25.png?v=1739470172"},{"product_id":"polyethylenimine-max-mw-40000-high-potency-linear-pei","title":"PEI MAX® - Transfection Grade Linear Polyethylenimine Hydrochloride (MW 40,000)","description":"\u003cp\u003ePolyethylenimine “Max” (PEI MAX) is a powerful, trusted, and cost-effective reagent widely considered as a current gold standard for both\u003cspan\u003e \u003c\/span\u003e\u003cem\u003ein vitro\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eand\u003cspan\u003e \u003c\/span\u003e\u003cem\u003ein vivo\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003etransfection. PEI MAX has a high density of protonatable amino groups, with amino nitrogen as every third atom. This imparts a high buffering ability at nearly any pH. Hence, once inside the endosome, PEI MAX disrupts the vacuole and releases the genetic material into the cytoplasm. Stable complexation with DNA, efficient entry into the cell, and ability to escape the endosome makes PEI MAX a highly efficient transfection reagent which is compatible for a wide range of cell lines\/types including the most commonly used HEK293 and CHO cells grown in adherent and suspension cultures. PEI MAX is capable of yielding high efficiency cell lines without compromising cell viability compared to other PEI and liposomal transfection reagents available in the market.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey Advantages\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSuperior Performance: High transfection efficiency with low cytotoxicity compared to other reagents on the market, suitable for use in larger concentrations and in sensitive cells.\u003c\/li\u003e\n\u003cli\u003eLow cytotoxicity: Even larger concentrations of PEI MAX disrupts cells minimally\u003c\/li\u003e\n\u003cli\u003eHigh Quality: Sourced and manufactured in the U.S. under ISO 13485 Quality System\u003c\/li\u003e\n\u003cli\u003eFlexible Workflow: Easy to optimize and introduce into application protocols. Scalable for well plates, flasks, and larger capacity bioreactors.\u003c\/li\u003e\n\u003cli\u003eAvailable in cGMP grade and in both powder and liquid formats.\u003c\/li\u003e\n\u003cli\u003eCost-Effective: Economical compared to similar transfection products in the market.\u003c\/li\u003e\n\u003cli\u003eHistory: Polysciences is a trusted partner for pharma and medical device key players with more than 60 years in specialty chemical manufacturing. PEI MAX has been used by thousands of customers in their research and development for more than a decade.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePOLYSCIENCES’ PEI MAX PRODUCT YIELDS HIGH TITERS OF AVV AFTER 72 HOURS POST TRANSFECTION\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/www.polysciences.com\/media\/wysiwyg\/PEI-hightiter-AVV.jpg\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFlasks containing 30mL cultures of suspension HEK293 cells at 1×10^6 cells\/mL were transfected to produce rAAV8 CMV-eGFP. rAAV8 was harvested from the media 48 hours post-transfection with increasing amounts of vector found in the media over time (Griger 2015).\u003c\/em\u003e\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"24765 (100) (100mg)","offer_id":46536959131862,"sku":"24765 (100)","price":0.0,"currency_code":"USD","in_stock":true},{"title":"24765 (1) (1g)","offer_id":46536959525078,"sku":"24765 (1)","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/peimax.png?v=1739470170"},{"product_id":"polyethylenimine-max-mw-4000-high-potency-linear-pei-1","title":"Polyethylenimine Hydrochloride, Linear (MW 4,000)","description":"\u003cp\u003e\u003cspan\u003ePolyethylenimine HCl, Linear, Mw 4,000 (L-PEI HCl 4000) is a fully hydrolyzed (deacylated), highly water soluble hydrochloride salt form of our Polyethylenimine, Linear, Mw 2,500 (\u003c\/span\u003e\u003ca href=\"https:\/\/polysciences.com\/products\/polyethylenimine-linear-mw-2-500-pei-2500\" title=\"Polyethylenimine, Linear, MW 2,500 (PEI 2500)\"\u003eCatalog # 24313\u003c\/a\u003e\u003ca href=\"https:\/\/www.polysciences.com\/default\/catalog\/product\/view\/id\/43188\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan\u003e). \u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eL-PEI 4000 is supplied as a hydrochloride salt for ease of handling and high water solubility. PEI 4000 can be converted into the linear free amine (L-PEI) form by neutralization with base containing longer contiguous ethyleneimine segments than L-PEI 2500.\u003c\/span\u003e\u003c\/p\u003e","brand":"Polysciences","offers":[{"title":"24885-2 (2 g)","offer_id":46536966766806,"sku":"24885-2","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/24885.jpg?v=1735675905"},{"product_id":"polyethylenimine-max-mw-160000-high-potency-linear-pei","title":"Polyethylenimine Hydrochloride, Linear (MW 160,000)","description":"\u003cdiv\u003e\n\u003cdiv class=\"description\"\u003e\n\u003cp\u003e\u003cspan\u003eLinear polyethylenimine is a highly-charged cationic polymer that readily binds highly anionic substrates. \u003c\/span\u003eIndustrially these polymeric amines are useful in many applications derived primarily from its polycationic character that allows it to tightly bind to negatively charged substrates.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Polysciences","offers":[{"title":"25439-2 (2 g)","offer_id":46536999698646,"sku":"25439-2","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/5258\/2358\/files\/pei-max.jpg?v=1735676358"}],"url":"https:\/\/polysciences.com\/collections\/polyethylenimine-pei.oembed?page=2","provider":"Polysciences","version":"1.0","type":"link"}