Methoxy PEG bromide, Mp 2000

Methoxy PEG bromide (mPEG-Br) is a monofunctional PEG derivative containing a bromide (-Br) group, enabling nucleophilic substitution (SN2) reactions and atom transfer radical polymerization (ATRP). Bromine functionality makes it highly useful for initiating polymerization, surface modifications, and covalent attachment to nucleophiles such as amines, thiols, and carboxylates.

Applications:
Controlled Radical Polymerization (CRP): Used as an initiator in ATRP, allowing for precise polymer chain growth and well-defined macromolecular architectures.
Polymer Grafting & Surface Functionalization: Reacts with amines and thiols to modify polymer backbones, nanoparticles, and surfaces for customizable coatings and drug carriers.
Bioconjugation & Material Functionalization: Enables covalent linkage to proteins, peptides, and biomolecules through nucleophilic substitution reactions.
Drug Delivery & Biointerfaces: Applied in biomaterials and smart drug carriers, where PEGylation enhances hydrophilicity and bioavailability.