NHS PEG Boc-amine alkyne, Mp 20000

NHS-PEG-Boc-Amine-Alkyne is a bifunctional PEG reagent containing an N-hydroxysuccinimide (NHS) ester for rapid amine coupling, a Boc-protected amine for controlled deprotection, and an alkyne group for click chemistry conjugation. This multifunctional linker allows for site-specific bioconjugation and stepwise modification strategies while maintaining excellent aqueous solubility.

Applications:
Bioconjugation: Couples efficiently to primary amines via NHS activation and enables alkyne-based click chemistry after Boc deprotection.
Surface Functionalization: Functionalizes biomaterials and nanomaterials with reactive alkyne groups for sequential conjugation strategies.
Hydrogels & Polymer Networks: Introduces protected amine and alkyne functionalities into hydrogel structures for dynamic and tunable bioactivity.