Beta-sitosterol

Beta-sitosterol is a naturally occurring sterol lipid that is growing in the bioprocessing space for its ability to improve mRNA transfection efficiency. Inclusion of beta-sitosterol in lipid nanoparticle (LNP) formulations has been shown to increase transfection efficiency rates both in cell cultures and in vivo, leading to particular interest in the use of the lipid in mRNA vaccine development. LNPs facilitate the safe and effective delivery of mRNA to target cells, thus enabling therapeutic action. Polysciences' high purity, synthetic, transfection grade beta-sitosterol can be used in conjunction with our other lipid products to provide reliable performance for a variety of bioprocessing applications.
>99% purity by HPLC-ELSDSYNONYMNS: β-sitosterol
Contact us at info.bp@polysciences.com to learn about our cGMP grade beta-sitosterol manufactured under 21 CFR part 210,211.