BioMag® Streptavidin

BioMag® Streptavidin

BioMag® Streptavidin consists of magnetic particles coated with streptavidin for high-affinity binding to biotinylated molecules. These particles are designed for rapid and efficient magnetic separation workflows, enabling isolation, purification, and manipulation of biomolecules without centrifugation.

Streptavidin binds biotin with extremely high affinity and specificity, making BioMag Streptavidin particles useful for capturing biotin-labeled proteins, nucleic acids, antibodies, and other biomolecules. Magnetic separation simplifies handling and reduces processing time in a wide range of laboratory protocols.

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Key Features & Benefits

• High-affinity streptavidin–biotin interaction: enables selective capture of biotinylated targets
• Magnetic separation: allows rapid isolation without centrifugation or filtration
• Efficient biomolecule recovery: supports purification and enrichment workflows
• Versatile binding platform: compatible with proteins, nucleic acids, and other biotinylated molecules
• Simplified workflow: reduces handling steps and improves reproducibility

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Product Details

• Product name: BioMag® Streptavidin
• Functionalization: Streptavidin-coated magnetic particles
• Binding interaction: Biotin–streptavidin affinity
• Separation method: Magnetic
• Form: Magnetic particle suspension
• Application type: Affinity capture and separation

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Typical Applications

Biotinylated protein purification
Capture and isolate biotin-labeled proteins using magnetic separation workflows.

Nucleic acid isolation
Used for separation of biotinylated DNA or RNA in molecular biology applications.

Immunoassays and detection systems
Supports assay development where biotin-streptavidin interactions are used for signal amplification or target capture.

Cell and biomolecule separation
Enables selective enrichment of targets labeled with biotinylated probes or antibodies.

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Functional Role

BioMag Streptavidin particles function as a magnetic affinity capture platform. Streptavidin immobilized on the particle surface binds biotinylated molecules with high specificity. Once bound, the particles can be separated from solution using a magnetic field, allowing rapid isolation of target molecules while unbound components are removed.

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Why Use Magnetic Streptavidin Particles?

Magnetic streptavidin particles combine the strength of the biotin–streptavidin interaction with the convenience of magnetic separation. This approach reduces reliance on centrifugation or column-based purification, enabling faster workflows and easier handling, particularly in multi-sample or high-throughput environments.

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Handling & Storage

• Store according to label instructions and recommended temperature conditions.
• Mix gently before use to ensure uniform particle suspension.
• Avoid freezing unless specified, as it may affect particle performance.
• Use appropriate laboratory practices and consult the SDS for detailed handling information.

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FAQ

Click a question to expand.

What is BioMag Streptavidin used for?

It is used for capturing and isolating biotinylated molecules such as proteins, DNA, and antibodies using magnetic separation.

How does streptavidin bind biotin?

Streptavidin binds biotin with very high affinity and specificity, making it useful for selective capture in biochemical workflows.

What are magnetic beads used for in biology?

Magnetic particles are used to isolate, purify, and manipulate biomolecules quickly using a magnetic field instead of centrifugation.

Can these particles be used with DNA or RNA?

Yes. Any biomolecule that is biotinylated, including nucleic acids, can be captured using streptavidin-coated magnetic particles.

Why use streptavidin instead of other binding systems?

The streptavidin–biotin interaction is one of the strongest known non-covalent interactions, providing reliable and specific binding.