Biotin PEG carboxylic acid, Mp 3000

Biotin PEG Carboxylic Acid is a functionalized polyethylene glycol (PEG) derivative that incorporates a biotin moiety at one end and a reactive carboxyl (-COOH) group at the other. The biotin functionality provides strong and specific binding to avidin or streptavidin proteins, making it ideal for bio-conjugation and surface modifications. The carboxyl end allows for further conjugation through standard amide bond formation using carbodiimide chemistry (e.g., EDC/NHS activation). This versatile PEG linker improves solubility, reduces non-specific interactions, and enhances biocompatibility.
Applications:
Bioconjugation: Enables covalent attachment of biotinylated molecules to proteins, peptides, and surfaces.
Drug Delivery Systems: Used for targeted biotin-mediated drug conjugates.
Surface Modification: Functionalizes nanoparticles, biosensors, and microfluidic devices.
Immunoassays & Diagnostics: Enhances biotin-streptavidin-based assay performance.