Biotin PEG OPSS, Mp 5000

Biotin PEG OPSS is a bioconjugation reagent featuring a biotin moiety for avidin/streptavidin affinity binding and an orthopyridyl disulfide (OPSS) group for thiol-exchange reactions. This thiol-reactive PEG derivative enables reversible biotinylation and controlled release in reducing environments, making it highly useful in affinity purification and biosensor applications.

Applications:
Hydrogel Functionalization: Allows reversible biotinylation in dynamic hydrogel systems.
Protein Labeling & Purification: Enhances biotin-streptavidin affinity assays and protein isolation techniques.
Nanoparticle Surface Modification: Functionalizes nanocarriers for targeted delivery and imaging.
Biosensor Development: Improves the sensitivity of biotin-based detection platforms.