Biotin PEG thiol, Mp 10000

Biotin PEG Thiol is a biotin-functionalized polyethylene glycol (PEG) derivative with a reactive thiol (-SH) group at one end. The biotin moiety enables strong and specific binding to avidin or streptavidin, making it highly useful for bio-recognition applications. The thiol group allows for covalent attachment to gold surfaces, maleimide-functionalized biomolecules, or self-assembled monolayers (SAMs), facilitating stable bioconjugation. The PEG spacer enhances solubility, minimizes steric hindrance, and reduces non-specific interactions, making it ideal for biomolecular labeling, sensor development, and targeted drug delivery.

Applications:
Biosensors & Diagnostics: Used in streptavidin-biotin affinity assays for enhanced sensitivity.
Nanoparticle & Surface Functionalization: Enables thiol-gold conjugation for stable immobilization on biosensor chips and nanoparticles.
Protein & Peptide Labeling: Facilitates site-specific bioconjugation to maleimide-containing biomolecules.
Drug Delivery & Targeting: Enhances bioavailability and specificity in targeted therapeutic applications.
Self-Assembled Monolayers (SAMs): Forms stable monolayers on gold and other surfaces for biointerfaces.