Boc-amine PEG carboxylic acid, Mp 5000

Boc-Amine PEG Carboxylic Acid is a bifunctional PEG derivative with a protected amine (-NH-Boc) at one end and a carboxyl (-COOH) group at the other. The carboxyl group allows for EDC/NHS-mediated conjugation to amine-containing biomolecules or surfaces, while the Boc-protected amine can be selectively deprotected under acidic conditions to reveal a reactive primary amine. This dual functionality makes it highly useful for multi-step bio-conjugation strategies and controlled surface modifications.

Applications:
Bioconjugation & Crosslinking: Enables sequential functionalization of biomolecules or surfaces.
Drug Delivery & PEGylation: Allows precise attachment of therapeutic agents for controlled release.
Surface Modification: Ideal for controlled tethering of biomolecules to nanoparticles and microfluidic chips.
Peptide & Protein Engineering: Useful for site-specific modifications in protein-protein interactions.