Product Description
Product Overview
Ethylene glycol diglycidyl ether (EGDGE), also known as Quetol 651 and EGDE, is a bifunctional water-soluble crosslinker used for carboxyl, amine, and hydroxyl functional polymers. The molecule contains two reactive epoxide groups that allow it to form covalent crosslinks with polymer systems and biomolecules.
Low chlorine content in our EGDGE makes it suitable for a wide range of applications including fiber modification, adhesives, paper treatment, and resin systems. EGDGE is also widely used as a crosslinking agent in biomaterial development.
EGDGE-crosslinked hydrogels are commonly used in sustained drug delivery systems and chromatographic separation of viruses and proteins.
Key Properties
- Bifunctional epoxy crosslinker for polymer and biomaterial modification
- Water-soluble molecule with two reactive epoxide groups
- Reactive toward carboxyl, amine, and hydroxyl functional polymers
- Low chlorine content suitable for diverse applications
- Weight per epoxide equivalent (WPE) ~113
- Total chlorine content: approximately 0.6%
Applications
Epoxy Resins
EGDGE can act as a reactive diluent and crosslinking agent in epoxy formulations where additional crosslink density or improved processing characteristics are desired.
Coatings and Adhesives
The crosslinking capability of EGDGE helps improve durability and adhesion in industrial coating and adhesive systems.
Biomedical Applications
EGDGE is frequently used in biomaterial development and hydrogel crosslinking. EGDGE-based hydrogels have been used in sustained drug delivery systems and in chromatographic separation of viruses and proteins.
Solubility & Compatibility
- Water-soluble crosslinking reagent
- Reactive with polymers containing carboxyl, amine, or hydroxyl functional groups
- Commonly used with polysaccharides, proteins, and synthetic polymers
Reaction efficiency and crosslink density will depend on polymer composition, functional group availability, and reaction conditions.
Preparation Tips
- Prepare solutions using clean, dry containers to avoid contamination
- Add crosslinker gradually when forming hydrogel systems
- Optimize concentration and reaction conditions for desired crosslink density
- Perform small-scale trials when developing new formulations
Handling & Storage
- Store in a cool, dry environment
- Keep container tightly closed when not in use
- Avoid moisture exposure during storage
- Follow standard laboratory chemical handling procedures
Frequently Asked Questions
Click a question to expand.
1. What is Ethylene Glycol Diglycidyl Ether used for?
EGDGE is used as a crosslinking agent for polymers containing carboxyl, amine, or hydroxyl functional groups. It is commonly used in epoxy formulations, biomaterial development, hydrogel preparation, and polymer modification.
2. What does EGDGE stand for?
EGDGE stands for Ethylene Glycol Diglycidyl Ether, a bifunctional epoxy crosslinking reagent.
3. What functional groups does EGDGE react with?
EGDGE reacts with nucleophilic functional groups such as carboxyl, amine, and hydroxyl groups, enabling crosslinking in many polymer systems.
4. Why is low chlorine content important in EGDGE?
Low chlorine content can improve compatibility and performance in certain polymer and resin systems and helps make the crosslinker suitable for a wider range of applications.
5. What research applications use EGDGE hydrogels?
EGDGE-crosslinked hydrogels are commonly used in sustained drug delivery systems and chromatographic separation of viruses and proteins.
Safety & Documentation
Follow standard laboratory safety practices when handling epoxy crosslinking reagents. Refer to the product Safety Data Sheet (SDS) for hazard information, recommended personal protective equipment, and safe handling guidance.
