Formaldehyde 37%, U.S.P. is a clear, colorless aqueous formaldehyde solution supplied for laboratory reagent use and the manufacture of substances. It is also commonly referred to as 37% formaldehyde solution, formalin 37%, or 37% formalin.
Product details: CAS 50-00-0; molecular formula CH2O; formaldehyde specification ≥34.5%; methanol specification 9.0–15.0%.
This methanol-stabilized solution may be used as a concentrated input in validated laboratory or manufacturing formulations that require aqueous formaldehyde. Confirm the required final concentration, buffer system, and methanol compatibility for the intended method before use.
This product is not paraformaldehyde powder and is not supplied as ready-to-use 10% neutral buffered formalin. Special handling charges and carrier surcharges apply.
Key Properties
- Nominal 37% aqueous formaldehyde solution
- U.S.P.-designated product
- Clear, colorless liquid
- Formaldehyde specification: ≥34.5%
- Methanol specification: 9.0–15.0%
- CAS 50-00-0; molecular formula CH2O
Applications
Laboratory Reagent Use
This solution is supplied for laboratory reagent workflows requiring a concentrated aqueous source of formaldehyde.
Chemical Manufacturing
It may be used in the manufacture of substances and in validated chemical processes where formaldehyde is required as a reactant or formulation component.
Formaldehyde-Containing Formulations
The concentrated solution can be used as a starting material when preparing laboratory or manufacturing formulations containing formaldehyde. Final concentration and composition should be confirmed using an established procedure.
Fixative Formulation Work
Concentrated formaldehyde solutions may be used as starting materials in validated fixative formulations. This product contains methanol and is not a prebuffered, ready-to-use histology fixative; verify the required buffer, concentration, and stabilizer content before use.
Composition & Use Considerations
- Formalin is a common name for an aqueous formaldehyde solution
- This product is a liquid formaldehyde solution, not solid paraformaldehyde
- Contains methanol as a stabilizing component
- Formalin products may differ in concentration, buffering, and methanol content
Review the product specification and applicable lot documentation before quantitative preparation. Do not substitute this material for methanol-free formaldehyde, paraformaldehyde, or neutral buffered formalin without confirming method compatibility.
Preparation & Use Considerations
- Use only with adequate ventilation or in a chemical fume hood
- Wear protective gloves, eye protection, and suitable protective clothing
- Follow a validated dilution or formulation procedure
- Avoid breathing vapors, mist, or spray
- Keep away from heat, sparks, open flames, and other ignition sources
Handling & Storage
- Store at room temperature; the product specification lists 20°C
- Keep in a well-ventilated area with the container tightly closed
- Store locked up and away from heat or ignition sources
- Minimize exposure to air, which can promote oxidation of formaldehyde to formic acid
- Avoid cold storage unless directed, as lower temperatures may promote formation of a white trioxymethylene precipitate
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FAQ
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1. What is 37% formaldehyde used for?
It is supplied for laboratory reagent use and the manufacture of substances. It may also be used as a concentrated input in validated formaldehyde-containing formulations.
2. Is 37% formaldehyde the same as formalin?
Formalin is a common name for an aqueous formaldehyde solution, typically containing approximately 37% formaldehyde by weight. Concentration, buffering, and stabilizer content can vary between formalin products.
3. Does this formaldehyde solution contain methanol?
Yes. The product specification lists a methanol content of 9.0–15.0%. Users should confirm that methanol is compatible with their intended procedure.
4. Is this paraformaldehyde or 10% neutral buffered formalin?
No. This product is a concentrated liquid formaldehyde solution. It is not solid paraformaldehyde and is not supplied as ready-to-use 10% neutral buffered formalin.
5. How should formaldehyde 37% be stored?
Store at room temperature in a well-ventilated area with the container tightly closed. Keep away from heat and ignition sources, minimize air exposure, and refer to the SDS for complete storage requirements.
Safety & Documentation
Formaldehyde 37%, U.S.P. is a hazardous mixture requiring appropriate engineering controls and personal protective equipment. The SDS identifies acute toxicity, skin irritation, serious eye damage, carcinogenicity, and flammability hazards. Use in a chemical fume hood or adequately ventilated area, avoid all direct exposure, and review the product specification and Safety Data Sheet before handling.
