⟡ Electron Microscopy / Histology & Immunochemical Fixatives
Glutaraldehyde, EM Grade, 8%
Glutaraldehyde, EM Grade, 8% is a high-purity aqueous glutaraldehyde solution designed for electron microscopy, histochemical, and immunological techniques. Supplied in convenient ampoules, this EM grade glutaraldehyde fixative supports consistent sample preparation where purity, stability, and preservation of fine cellular structure are important.
Polysciences developed a superior grade of glutaraldehyde suitable for immunochemical techniques. Each batch of vacuum-distilled glutaraldehyde manufactured by Polysciences is analyzed to maintain consistent quality and to help minimize contaminants that may interfere with antigenicity or sample integrity.
Key Features & Benefits
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EM grade glutaraldehyde: recommended for electron microscopy, histochemical, and immunological techniques
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8% aqueous solution: supplied at a defined concentration for laboratory fixation workflows
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High-purity, vacuum-distilled material: manufactured and analyzed for consistency from batch to batch
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Designed to support antigen preservation: helps reduce contaminants that can affect antigenicity in immunochemical applications
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Clear, colorless solution: Polysciences EM grade glutaraldehydes are described in published studies as practically free of undesirable polymeric product impurities
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Ampoule packaging: each ampoule is fitted with an ampoule cracker for added safety and convenience
Product Details
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Product name: Glutaraldehyde, EM Grade, 8%
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CAS number: 111-30-8
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Product number: 00216
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Available sizes: 30 x 10 mL and 10 x 10 mL ampoules
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Storage: Store at 4°C
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Handling: Use gloves, chemical goggles, and a fume hood
Typical Applications
Electron microscopy fixation
Glutaraldehyde is widely used as a primary fixative for electron microscopy sample preparation because it rapidly crosslinks proteins and helps preserve ultrastructural detail.
Histochemical techniques
EM grade glutaraldehyde is used in histochemical workflows where consistent fixation and preservation of cellular and tissue architecture are required.
Immunological and immunochemical techniques
Polysciences EM grade glutaraldehyde is designed for applications where contaminant control and antigen preservation are important considerations.
Biological specimen preparation
This 8% glutaraldehyde solution is suitable for laboratory fixation workflows involving cells, tissues, and other biological samples prepared for microscopy-based analysis.
Functional Role
Glutaraldehyde is a dialdehyde fixative that reacts primarily with amine-containing biomolecules, including proteins. Through crosslinking reactions, it helps stabilize biological structures during fixation and sample processing. In electron microscopy and histology workflows, this crosslinking action supports preservation of fine structural detail for downstream imaging and analysis.
Why EM Grade Glutaraldehyde Matters
The quality of glutaraldehyde can affect fixation performance, background, reproducibility, and preservation of antigenicity. EM grade glutaraldehyde is selected when researchers need a high-purity fixative with low levels of interfering impurities. Polysciences offers highly purified 8%, 25%, 50%, and 70% EM Grade glutaraldehyde solutions that are clear, colorless, and practically free of undesirable polymeric product impurities.
Handling & Storage
- Store at 4°C.
- Keep container tightly sealed until use.
- Use appropriate personal protective equipment, including gloves and chemical goggles.
- Handle in a chemical fume hood.
- Consult the SDS and product specification sheet before handling, preparing, or using this product.
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FAQ
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What is Glutaraldehyde, EM Grade, 8% used for?
Glutaraldehyde, EM Grade, 8% is used as a high-purity fixative for electron microscopy, histochemical, immunological, and immunochemical techniques.
Why choose EM grade glutaraldehyde?
EM grade glutaraldehyde is selected when purity and consistency are important for fixation performance. It is intended to help minimize impurities that may interfere with sample preservation, antigenicity, or microscopy results.
What is the CAS number for glutaraldehyde?
The CAS number for glutaraldehyde is 111-30-8.
How should Glutaraldehyde, EM Grade, 8% be stored?
This product should be stored at 4°C in the original container. Refer to the SDS and product specification sheet for complete storage and handling guidance.
What precautions should be used when handling glutaraldehyde?
Glutaraldehyde should be handled with appropriate personal protective equipment, including gloves and chemical goggles, and used in a chemical fume hood. Always review the SDS before use.
What package format is available for this product?
Glutaraldehyde, EM Grade, 8% is available in ampoule packaging, including 30 x 10 mL and 10 x 10 mL formats. Each ampoule includes an ampoule cracker for added safety and convenience.
