Modified Davidson's Fixative (Hartmann's Fixative)

Modified Davidson's Fixative is a superior alternative to Bouin's Fixative. Not only is it safer, but it also produces less shrinkage and superior overall morphologic detail compared to Bouin's when used to fix testes for routine histopathological examination. Modified Davidson's Fixative is used routinely for optimum fixation of eyes. It can support excellent staining of acrosomes with periodic acid-Schiff (PAS) reagent when staging of spermatogenesis is required.1

Modified Davidson’s Fixative is also known for the visualization of lymph nodes in radical dissection specimens. In both breast and colon specimens it aids in visualization by turning the lymph nodes white.