Hydroxyl PEG azide, Mp 3000

Hydroxyl PEG Azide (HO-PEG-N₃) is a heterobifunctional PEG derivative featuring a terminal hydroxyl (-OH) and an azide (-N₃) group. The hydroxyl end allows for further functionalization, while the azide enables bio-orthogonal click chemistry reactions with alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC). This makes it a powerful tool for bioconjugation, hydrogel crosslinking, and nanoparticle modification.

Applications:

Click Chemistry & Bioconjugation: Forms stable triazole linkages with alkyne-functionalized molecules.
Hydrogel & Scaffold Engineering: Enables highly efficient crosslinking in polymeric and biomaterial networks.
Nanoparticle Functionalization: Provides bio-orthogonal coatings for enhanced drug delivery systems.
Biosensor & Surface Coatings: Functionalizes surfaces for targeted biomolecule capture.