Hydroxystilbamidine (Fluoro Gold) is a highly sensitive fluorescent tracer widely used in neuroscience and neuroanatomical research. It is recognized as one of the most effective retrograde neuronal tracers, enabling researchers to identify and map neuronal pathways through efficient uptake and transport within the nervous system. Fluoro Gold produces bright, long-lasting fluorescence and provides excellent labeling of neuronal cell bodies and processes, making it an invaluable tool for nerve tracing, neural connectivity studies, and regeneration research.
Key Features & Benefits
High-sensitivity fluorescent neuronal tracer for retrograde labeling.
Bright and durable fluorescence for clear visualization of labeled neurons.
Efficient retrograde axonal transport and neuronal uptake.
Excellent neuronal cell body and dendritic labeling.
Suitable for long-term tracing studies due to stable labeling.
Compatible with many histological and immunohistochemical techniques.
Widely cited and validated in academic and biomedical research.
Typical Applications
Neuroscience Research
Retrograde neuronal pathway tracing
Neural circuit mapping
Motor and sensory neuron identification
Brain and spinal cord connectivity studies
Nerve Regeneration Studies
Evaluation of peripheral nerve repair
Assessment of axonal regeneration
Functional recovery investigations
Histology & Imaging
Fluorescence microscopy
Confocal microscopy
Two-photon microscopy
Neuroanatomical characterization
Academic & Biomedical Research
Central nervous system (CNS) studies
Peripheral nervous system (PNS) studies
Neurodegenerative disease research
Developmental neuroscience
Use Guidance
Prepare solutions using distilled water or physiological saline as appropriate for the application.
Typical working concentrations range from 1% to 10%; optimization may be required depending on the experimental design.
Apply using established injection or labeling protocols suitable for the target tissue and species.
Protect solutions and labeled samples from prolonged exposure to light to minimize photobleaching.
Researchers should validate staining conditions and imaging parameters for their specific application.
Handling & Storage
Handling
For research use only. Wear appropriate personal protective equipment (PPE), including laboratory gloves, protective clothing, and safety glasses.
Avoid inhalation, ingestion, and direct contact with skin or eyes.
Handle according to established laboratory safety procedures.
Storage
Store dry material in a tightly sealed, light-protected container at approximately 4°C.
Prepared solutions should also be stored in light-protected containers at 4°C.
Protect from excessive heat, moisture, and direct sunlight.
When stored properly, dry material typically maintains stability for more than one year.
Typical Properties
Appearance: Yellow to golden-yellow powder
Application: Fluorescent retrograde neuronal tracer
Solubility: Water and saline solutions
Detection Method: Fluorescence microscopy
Research Grade: For laboratory and research applications only
