Iodoacetamide PEG alkyne, Mp 3000

Iodoacetamide PEG Alkyne is a bifunctional PEG derivative containing an iodoacetamide (-C(O)NHI) group for thiol-specific conjugation and a terminal alkyne (-C≡CH) for click chemistry applications. It enables the dual modification of biomolecules, surfaces, and polymers while maintaining high solubility and low toxicity.

Applications:
Hydrogel Formation: Used in thiol-alkyne and click crosslinking strategies for bioresponsive hydrogels.
Protein & Peptide Modification: Allows thiol-specific bioconjugation followed by azide-alkyne click reactions.
Nanoparticle Functionalization: Enhances surface tunability of nanoparticles for biomedical applications.
Biomedical Surface Coatings: Improves anti-fouling properties and functionalization versatility.