Maleimide PEG biotin, Mp 5000

Maleimide PEG Biotin is a heterobifunctional PEG linker with a maleimide (-C=CH-NH-C(O)-) group for thiol conjugation and a biotin moiety for avidin or streptavidin binding. This reagent provides a highly efficient way to biotinylate proteins, peptides, and nanoparticles while maintaining aqueous solubility and reducing steric hindrance.

Applications:
Hydrogel Functionalization: Enables site-selective biotinylation for affinity-based hydrogel systems.
Protein Labeling & Detection: Used in biotin-streptavidin assays for enhanced signal amplification.
Nanobiotechnology: Functionalizes nanoparticles for bioassays and targeted imaging.
Surface Immobilization: Improves biotinylation strategies for biosensors and diagnostic platforms.