Maleimide PEG NHS, Mp 5000

Maleimide PEG NHS is a bifunctional polyethylene glycol (PEG) derivative containing a maleimide (-C=CH-NH-C(O)-) group for thiol-specific conjugation and an N-hydroxysuccinimide (NHS) ester for amine coupling. This dual-reactive PEG linker is widely used for bioconjugation, drug delivery, and surface modifications, enabling site-specific crosslinking of biomolecules while maintaining hydrophilicity and biocompatibility.

Applications:
Hydrogel Crosslinking: Used in thiol-maleimide and NHS-amine chemistry to form biofunctionalized hydrogels.
Protein & Peptide Labeling: Allows dual-functional conjugation for targeted drug delivery systems.
Nanoparticle Functionalization: Enhances bioconjugation strategies for imaging and therapeutic carriers.
Surface Coatings: Improves antifouling properties and functionalization of biomaterial surfaces.