Nonenyl Succinic Anhydride (NSA), EM Grade, is a liquid anhydride used for curing low-viscosity embedding resin for electron microscopy. It is particularly used in Spurr formulations and is specially distilled for E.M. applications.
Developed in conjunction with Dr. Spurr, NSA supports resin systems used in electron microscopy sample preparation where controlled curing, low-viscosity embedding performance, and formulation consistency are important.
Key Properties
- Liquid anhydride for curing low-viscosity embedding resin
- EM Grade material specially distilled for electron microscopy applications
- Particularly used in Spurr resin formulations
- Product Number: 01542
- CAS Number: 28928-97-4
- Linear formula: C13H20O3
- Molecular weight: 224
- Refractive index: n20/D 1.476
- Appearance: Tan to yellow liquid, free from haze and particulate matter
- Available sizes: 450 g and 4 x 450 g
Applications
Electron Microscopy Embedding
Used in low-viscosity embedding resin systems for electron microscopy sample preparation.
Spurr Resin Formulations
Particularly used in Spurr formulations where a liquid anhydride curing component is required.
Resin Curing Systems
Supports curing of compatible embedding resin formulations used in microscopy and histology-related workflows.
Laboratory Sample Preparation
Useful for laboratories preparing resin-embedded specimens for sectioning, imaging, and ultrastructural analysis.
Compatibility & Formulation Considerations
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Material type: Liquid anhydride curing component
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Primary use: Low-viscosity embedding resin systems for E.M.
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Formulation use: Spurr-type resin formulations and compatible embedding resin systems
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Appearance requirement: Tan to yellow liquid, free from haze and particulate matter
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Performance factors: Cure behavior and final resin properties depend on resin composition, mixing ratio, temperature, and processing conditions
Evaluate compatibility and cure performance under the intended embedding protocol before routine use.
Preparation Tips
- Use the resin formulation and mixing sequence specified by the validated electron microscopy embedding protocol.
- Measure components carefully to support consistent curing and embedding performance.
- Mix thoroughly while minimizing unnecessary air incorporation.
- Protect working mixtures from contamination, moisture, and incompatible materials.
- Document resin composition, mixing ratio, temperature, cure schedule, and sample preparation conditions for reproducible results.
Handling & Storage
- Wear gloves and chemical goggles when handling.
- Use in a well-ventilated area and avoid skin and eye contact.
- Store at room temperature.
- Keep container tightly closed when not in use.
- Protect from contamination and unnecessary moisture exposure.
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Frequently Asked Questions
1. What is Nonenyl Succinic Anhydride (NSA) used for?
NSA is used as a liquid anhydride curing component for low-viscosity embedding resin systems used in electron microscopy sample preparation.
2. Is this NSA product suitable for Spurr formulations?
Yes. This EM Grade NSA is particularly used in Spurr formulations for electron microscopy embedding resin systems.
3. What does EM Grade mean for this product?
EM Grade indicates that the material is prepared for electron microscopy applications. This NSA is specially distilled for E.M. use.
4. What is the CAS number for Nonenyl Succinic Anhydride?
The CAS number for this product is 28928-97-4.
5. What is the appearance of this product?
This product is supplied as a tan to yellow liquid that is free from haze and particulate matter.
6. How should Nonenyl Succinic Anhydride be stored?
Store at room temperature, keep the container tightly closed when not in use, and protect from contamination and unnecessary moisture exposure.
Safety & Documentation
Handle with gloves, chemical goggles, appropriate PPE, and standard laboratory practices. Refer to the Safety Data Sheet (SDS), product documentation, and Certificate of Analysis for handling, storage, safety, and lot-specific guidance.
