⟡ EM Fixatives / Formaldehyde Preparation / Histology Reagents
Paraformaldehyde, EM Grade is a polymerized formaldehyde reagent commonly used for preparation of formaldehyde fixation solutions in microscopy, histology, and biological specimen preservation workflows. Upon depolymerization in water, paraformaldehyde generates formaldehyde solutions suitable for tissue fixation and morphology preservation applications.
This EM grade material is widely used in electron microscopy and laboratory fixation protocols requiring consistent formaldehyde solution preparation and reliable specimen fixation performance.
Key Features & Benefits
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EM grade paraformaldehyde: suitable for microscopy and fixation workflows
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Produces formaldehyde solutions: depolymerizes in water for fixative preparation
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Consistent fixation quality: supports reproducible specimen preservation procedures
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Widely used laboratory fixative reagent: suitable for histology and microscopy applications
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Compatible with fixation protocols: commonly used in tissue preservation workflows
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Useful for EM applications: suitable for electron microscopy specimen preparation
Product Details
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Product name: Paraformaldehyde
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Grade: EM Grade
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Chemistry: Polymerized formaldehyde fixation reagent
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Applications: Formaldehyde solution preparation, tissue fixation, microscopy, histology, electron microscopy specimen preparation
Typical Applications
Fixative preparation
Used to prepare formaldehyde fixation solutions for biological specimen preservation workflows.
Electron microscopy specimen preparation
Suitable for EM fixation and tissue preparation procedures requiring formaldehyde-based fixation.
Histology & microscopy
Commonly utilized in tissue fixation workflows for microscopy and histological analysis.
Research laboratory workflows
Frequently used in biological research laboratories requiring freshly prepared formaldehyde solutions.
Functional Properties
Paraformaldehyde depolymerizes in heated water to generate formaldehyde solutions used in biological fixation procedures. Proper preparation helps produce consistent fixative solutions for microscopy applications.
To achieve a strong solution, fixation protocols commonly involve heating the water to approximately 60°C followed by careful addition of sodium hydroxide solution dropwise during preparation.
Why Use Paraformaldehyde, EM Grade?
Paraformaldehyde, EM Grade is widely used for preparation of fresh formaldehyde fixative solutions in microscopy and biological specimen preservation workflows.
Its broad use in electron microscopy, histology, and tissue fixation laboratories makes it a standard reagent for formaldehyde-based fixation procedures.
Handling & Storage
- Store in a cool, dry, well-ventilated laboratory environment.
- Keep containers tightly sealed when not in use.
- Handle using appropriate laboratory protective equipment.
- Prepare fixative solutions in properly ventilated areas.
- Consult the SDS for complete safety, storage, and handling information.
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FAQ
Click a question to expand.
What is Paraformaldehyde, EM Grade used for?
It is used to prepare formaldehyde fixation solutions for microscopy, histology, and electron microscopy specimen preparation workflows.
How is paraformaldehyde converted into formaldehyde solution?
Paraformaldehyde depolymerizes in heated water to generate formaldehyde fixation solutions.
Why is sodium hydroxide added during preparation?
Sodium hydroxide solution may be added dropwise during preparation to help achieve a strong, clear formaldehyde solution.
Is this material suitable for electron microscopy workflows?
Yes. This EM grade paraformaldehyde is suitable for electron microscopy fixation and specimen preparation applications.
What temperature is commonly used during solution preparation?
Preparation protocols commonly involve heating water to approximately 60°C prior to depolymerization.
