Poly(Caprolactone-co-glycolide), 30:70, IV 1.6 dL/g, Powder

Poly(Caprolactone - co - glycolide), 30:70, IV 1.6 dL/g, Powder - Polysciences
Poly(Caprolactone - co - glycolide), 30:70, IV 1.6 dL/g, Powder - Polysciences
Product Number:
50376

Size

Price

$327.54

Quantity

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Product Specifications
Linear Formula
    (C6H10O2)m(C2H2O2)n 
Appearance
    White to off-white to light tan powder
Biodegradation Time
    Months
Synonyms
    PCL/PGA
    PCL-co-PGA
    PCL and PGA Copolymer
    PCLGA
Safety Data Sheet (SDS)
Handling
    Gloves & fume hood
Storage
    Protect from moisture. Store at -20°C.
Hazards
    Harmless - use normal precautions; Hygroscopic
Related Documents

    No Related Documents

References

    1. Cui, H., & Sinko, P. J. (2012). The role of crystallinity on differential attachment/proliferation of osteoblasts and fibroblasts on poly (caprolactone-co-glycolide) polymeric surfaces. Frontiers of Materials Science, 6, 47-59.

    2. Jiang, Z., You, Y., Deng, X., & Hao, J. (2007). Injectable hydrogels of poly (ɛ-caprolactone-co-glycolide)–poly (ethylene glycol)–poly (ɛ-caprolactone-co-glycolide) triblock copolymer aqueous solutions. Polymer, 48(16), 4786-4793.

    3. Wischke, C., Löbler, M., Neffe, A. T., Hanh, B. D., Zierke, M., Sternberg, K., ... & Lendlein, A. (2011, December). A Blend of Poly (ε‐caprolactone) and Poly [(ε‐caprolactone)‐co‐glycolide] with Remarkable Mechanical Features and Wide Applicability as Biomaterial. In Macromolecular Symposia (Vol. 309, No. 1, pp. 59-67). Weinheim: WILEY‐VCH Verlag.

Product Description

High-grade, suitable for biomedical research.
Supplied as micronized powder.

Poly(Caprolactone-co-glycolide) (PCLGA) is a biodegradable and biocompatible copolymer made by the copolymerization of the monomers caprolactone and glycolide. PCLGA has a wide range of potential applications in the biomedical and pharmaceutical industries including medical devices, tissue engineering, 3D printing, and controlled release implants.

The monomer ratio of PCLGA has a significant impact on the degradation rate of the material with a higher proportion of glycolide leading to more rapid degradation rate due to the glycolide having a greater degree of hydrophilicity and lower crystallinity compared to caprolactone, thus making it more susceptible to hydrolysis and enzymatic degradation.

We offer several PCLGA products of varying monomer ratios and molecular weights.
Synonyms/Acronyms:
PCL/PGA PCL-co-PGA PCL and PGA Copolymer PCLGA
Poly(Caprolactone - co - glycolide), 30:70, IV 1.6 dL/g, Powder - Polysciences
Poly(Caprolactone - co - glycolide), 30:70, IV 1.6 dL/g, Powder - Polysciences
Product Specifications
Linear Formula
    (C6H10O2)m(C2H2O2)n 
Appearance
    White to off-white to light tan powder
Biodegradation Time
    Months
Synonyms
    PCL/PGA
    PCL-co-PGA
    PCL and PGA Copolymer
    PCLGA
Safety Data Sheet (SDS)
Handling
    Gloves & fume hood
Storage
    Protect from moisture. Store at -20°C.
Hazards
    Harmless - use normal precautions; Hygroscopic
Related Documents

    No Related Documents

References

    1. Cui, H., & Sinko, P. J. (2012). The role of crystallinity on differential attachment/proliferation of osteoblasts and fibroblasts on poly (caprolactone-co-glycolide) polymeric surfaces. Frontiers of Materials Science, 6, 47-59.

    2. Jiang, Z., You, Y., Deng, X., & Hao, J. (2007). Injectable hydrogels of poly (ɛ-caprolactone-co-glycolide)–poly (ethylene glycol)–poly (ɛ-caprolactone-co-glycolide) triblock copolymer aqueous solutions. Polymer, 48(16), 4786-4793.

    3. Wischke, C., Löbler, M., Neffe, A. T., Hanh, B. D., Zierke, M., Sternberg, K., ... & Lendlein, A. (2011, December). A Blend of Poly (ε‐caprolactone) and Poly [(ε‐caprolactone)‐co‐glycolide] with Remarkable Mechanical Features and Wide Applicability as Biomaterial. In Macromolecular Symposia (Vol. 309, No. 1, pp. 59-67). Weinheim: WILEY‐VCH Verlag.