Poly(D,L-lactide-co-glycolide), 50:50, IV 0.4 dL/g, Ester terminated, Powder

Product Number:

CAS #

CAS # Product #

50329

26780-50-7

Size

Price

$225.00

Quantity

Bulk Request

Request a Bulk Quote

Product Specifications

Spec-50329.pdf

Linear Formula

[C3H4O2]n[C2H2O2]m

Appearance

White to off-white to light tan powder

Biodegradation Time

Months

Synonyms

Viscosity

~0.4 dL/g

Soluble In

Chloroform, acetone, ethyl acetate, tetrahydrofuran

Functional Group

Ester

Safety Data Sheet (SDS)

No SDS

Handling

Gloves & fume hood

Storage

Protect from moisture. Store at -20°C.

Hazards

Harmless - use normal precautions; Hygroscopic

Hazard Code

N/A

Related Documents

1. Islam, M.S.; Mitra, S. Synthesis of Microwave Functionalized, Nanostructured Polylactic Co-Glycolic Acid (nfPLGA) for Incorporation into Hydrophobic Dexamethasone to Enhance Dissolution. Nanomaterials 2023, 13, 943.

2. Serris, I., Serris, P., Frey, K.M. et al. Development of 3D-Printed Layered PLGA Films for Drug Delivery and Evaluation of Drug Release Behaviors. AAPS PharmSciTech 21, 256 (2020).

3. Middleton, John C., and Arthur J. Tipton. 2000. "Synthetic Biodegradable Polymers as Orthopedic Devices. Biomaterials 21 (23): 2335“46. doi:10.1016/S0142-9612(00)00101-0.

4. Grayson, Amy C Richards, Insung S Choi, Betty M Tyler, Paul P Wang, Henry Brem, Michael J Cima, and Robert Langer. 2003. Multi-Pulse Drug Delivery from a Resorbable Polymeric Microchip Device. Nature Materials 2 (11). Nature Publishing Group: 767“72. doi:10.1038/nmat998.

5. Dawes, G J S, L E Fratila-Apachitei, K Mulia, I Apachitei, G-J Witkamp, and J Duszczyk. 2009. Size Effect of PLGA Spheres on Drug Loading Efficiency and Release Profiles. Journal of Materials Science: Materials in Medicine 20 (5). Springer: 1089“94. doi:10.1007/s10856-008-3666-0.

Poly(D,L - lactide - co - glycolide), 50:50, IV 0.4 dL/g, Ester terminated, Powder - Polysciences

Product Description

High-grade, suitable for biomedical research.
Supplied as micronized powder.

Poly(lactide-co-glycolide) (PLGA) is a biodegradable copolymer composed of lactide and glycolide monomers. Its physical and chemical properties can be tailored by adjusting the ratio of the two monomers with a higher glycolide content ratio degrading faster and a higher lactide content ratio degrading slower.

PGLA is widely used in medical applications, such as sutures, drug delivery systems, 3D printing, and tissue engineering, due to its excellent biocompatibility and controlled biodegradability. It is also used in the pharmaceutical industry as a biodegradable polymer matrix for drug delivery systems and in the food industry as a biodegradable packaging material.