Poly(D,L-lactide-co-glycolide), 50:50, IV 0.6 dL/g

Product Number:

CAS #

CAS #                 Product #

    23986
    26780-50-7

Size

Price

$48.00

Quantity

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Product Specifications
Safety Data Sheet (SDS)
Related Documents
References

    1. Middleton, John C., and Arthur J. Tipton. 2000. "Synthetic Biodegradable Polymers as Orthopedic Devices.” Biomaterials 21 (23): 2335–46. doi:10.1016/S0142-9612(00)00101-0.

    2. Grayson, Amy C Richards, Insung S Choi, Betty M Tyler, Paul P Wang, Henry Brem, Michael J Cima, and Robert Langer. 2003. “Multi-Pulse Drug Delivery from a Resorbable Polymeric Microchip Device.” Nature Materials 2 (11). Nature Publishing Group: 767–72. doi:10.1038/nmat998.

    3. Dawes, G J S, L E Fratila-Apachitei, K Mulia, I Apachitei, G-J Witkamp, and J Duszczyk. 2009. “Size Effect of PLGA Spheres on Drug Loading Efficiency and Release Profiles.” Journal of Materials Science: Materials in Medicine 20 (5). Springer: 1089–94. doi:10.1007/s10856-008-3666-0.

Poly(D,L - lactide - co - glycolide), 50:50, IV 0.6 dL/g - Polysciences
Poly(D,L - lactide - co - glycolide), 50:50, IV 0.6 dL/g - Polysciences

Product Description


Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).1 The control of these properties makes PLGA especially well suited for applications where medical devices are only needed for weeks (e.g. drug delivery).

Synonyms: PDLGA, PLGA, DL-PLGA

Specifications


Inherent Viscosity (ηinh): 0.50 - 0.65 dL/g

Properties


Soluble in: dichloromethane (DCM), tetrahydrofuran (THF), ethyl acetate, acetone

Poly(D,L - lactide - co - glycolide), 50:50, IV 0.6 dL/g - Polysciences
Poly(D,L - lactide - co - glycolide), 50:50, IV 0.6 dL/g - Polysciences
Product Specifications
Synonyms
    PDLGA
    PLGA
    DL-PLGA
    Lactide and Glycolide Copolymer
Viscosity
    ~0.6 dL/g
Glass Transition Temperature (Tg)
    45 - 50°C
Soluble In
    Chloroform, DMSO, dichloromethane, acetone, ethyl acetate, tetrahydrofuran
Safety Data Sheet (SDS)
Handling
    Exercise normal care
Storage
    Protect from moisture. Store at -20°C
Hazards
    Irritant
    Hygroscopic
Hazard Code
    HK2bg
Related Documents
References

    1. Middleton, John C., and Arthur J. Tipton. 2000. "Synthetic Biodegradable Polymers as Orthopedic Devices.” Biomaterials 21 (23): 2335–46. doi:10.1016/S0142-9612(00)00101-0.

    2. Grayson, Amy C Richards, Insung S Choi, Betty M Tyler, Paul P Wang, Henry Brem, Michael J Cima, and Robert Langer. 2003. “Multi-Pulse Drug Delivery from a Resorbable Polymeric Microchip Device.” Nature Materials 2 (11). Nature Publishing Group: 767–72. doi:10.1038/nmat998.

    3. Dawes, G J S, L E Fratila-Apachitei, K Mulia, I Apachitei, G-J Witkamp, and J Duszczyk. 2009. “Size Effect of PLGA Spheres on Drug Loading Efficiency and Release Profiles.” Journal of Materials Science: Materials in Medicine 20 (5). Springer: 1089–94. doi:10.1007/s10856-008-3666-0.