⟡ PEGDA 20000 / Hydrogel Crosslinkers / Biomaterials Research
Poly(ethylene glycol) diacrylate (PEGDA 20000) is a high molecular weight hydrophilic macromer containing terminal acrylate groups for free-radical crosslinking and hydrogel formation. Its polyethylene glycol backbone supports water solubility, flexibility, and biocompatibility, making PEGDA widely used in biomaterials research, tissue engineering, photopolymerization, and soft polymer network design.
The higher molecular weight of PEGDA 20000 enables formation of soft, highly swollen hydrogel systems with lower crosslink density and increased mesh size. These characteristics make it especially useful for diffusion-sensitive biomaterials, drug delivery research, and flexible hydrogel architectures.
Key Features & Benefits
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Bifunctional PEG macromer: supports efficient UV and radical crosslinking
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Hydrophilic polymer backbone: enables hydrogel formation and aqueous compatibility
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High molecular weight PEGDA: suitable for soft and highly flexible polymer networks
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Tunable swelling behavior: supports customizable hydrogel permeability and mechanics
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Widely used in biomaterials: ideal for tissue engineering and soft material research
Product Details
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Product name: Polyethylene Glycol Diacrylate (PEGDA 20000)
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Abbreviation: PEGDA
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Molecular weight: Approx. 20,000 Da
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Chemistry: Polyethylene glycol terminated with acrylate functional groups
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Crosslinking mechanism: Free-radical and photopolymerization chemistry
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Applications: Hydrogels, biofabrication, drug delivery, coatings, and biomaterials research
Typical Applications
Hydrogel systems
PEGDA 20000 is commonly used to produce soft hydrogels for tissue engineering, wound healing research, cell encapsulation, and controlled release studies.
Drug delivery research
The large mesh size and swelling behavior of PEGDA 20000 hydrogels support diffusion-sensitive drug delivery and biomolecule transport applications.
3D bioprinting & photopolymerization
Frequently incorporated into photocurable bioink and hydrogel formulations for soft tissue engineering and precision fabrication workflows.
Microfluidics & soft materials
Used in flexible polymer networks and hydrogel matrices for lab-on-a-chip systems and soft device fabrication.
Functional Properties
The polyethylene glycol backbone contributes hydrophilicity, flexibility, and low protein adsorption characteristics, while the terminal acrylate groups enable rapid polymer network formation through UV or radical initiation.
Compared to lower molecular weight PEGDA materials, PEGDA 20000 generally forms softer hydrogels with lower crosslink density, greater elasticity, and increased swelling capacity. These properties are valuable in applications requiring gentle mechanical environments and enhanced molecular diffusion.
Why Use PEGDA 20000?
PEGDA 20000 is commonly selected for hydrogel and biomaterials applications requiring soft polymer mechanics, tunable permeability, and highly hydrated polymer networks. Researchers use PEGDA systems to tailor hydrogel stiffness, transport behavior, and structural flexibility.
Its compatibility with photopolymerization workflows and advanced hydrogel engineering makes PEGDA 20000 a versatile material for biomaterials science, biofabrication, and soft polymer research.
Handling & Storage
- Store in a cool, dry environment away from heat and direct light.
- Keep containers tightly sealed to minimize premature polymerization.
- Avoid prolonged UV exposure and contamination with radical initiators.
- Use appropriate personal protective equipment during handling.
- Consult the SDS for complete handling and safety information.
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FAQ
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What is PEGDA 20000 used for?
PEGDA 20000 is commonly used in hydrogels, tissue engineering, drug delivery research, biofabrication, and soft biomaterials applications.
What does PEGDA stand for?
PEGDA stands for poly(ethylene glycol) diacrylate, a PEG-based macromer with terminal acrylate functional groups.
Why use high molecular weight PEGDA?
Higher molecular weight PEGDA materials generally form softer hydrogels with larger mesh sizes, greater flexibility, and increased swelling behavior.
How does PEGDA crosslink?
PEGDA crosslinks through free-radical polymerization, often initiated using UV light and photoinitiator systems.
Where can I buy PEGDA 20000?
Polysciences supplies PEGDA 20000 materials for hydrogel development, biomaterials research, and polymer engineering applications.