Poly(ethylene glycol) diacrylate (PEGDA 35K) is a high molecular weight PEG-based macromer used in hydrogel formation, polymer network synthesis, and biomaterials research. Terminal acrylate groups enable free-radical crosslinking to form hydrophilic polymer networks with tunable swelling and mechanical properties.
Synonyms and related names: PEGDA 35K, polyethylene glycol diacrylate 35000, PEG diacrylate MW 35000, PEG hydrogel crosslinker.
Compared with lower molecular weight PEGDA grades, PEGDA 35K contains longer polyethylene glycol chains between reactive acrylate groups. This can support formation of softer, more flexible hydrogel structures with lower crosslink density and increased swelling capacity under comparable formulation conditions.
PEGDA-based hydrogels are widely investigated in drug delivery systems, tissue engineering, photopolymer synthesis, microfluidics, coatings, and polymerizable biomaterials where controlled hydrogel mechanics and permeability are important.
Key Properties
- High molecular weight PEG-based diacrylate macromer
- Terminal acrylate groups support free-radical polymerization
- Hydrophilic polyethylene glycol backbone
- Useful for flexible hydrogel and polymer network formation
- Supports tunable swelling and mechanical properties
- Widely used in biomaterials and hydrogel research
Applications
Hydrogel Formation
PEGDA 35K is commonly used to prepare hydrophilic crosslinked hydrogels with tunable swelling behavior and flexible network structures.
Drug Delivery & Biomaterials
Crosslinked PEGDA hydrogels are frequently evaluated as carrier matrices and biomaterials for controlled release and tissue engineering research.
Photopolymer & Polymer Network Synthesis
The terminal acrylate groups enable light-initiated and chemically initiated polymerization for formation of uniform polymer networks.
Microfluidics & Advanced Materials
PEGDA materials are widely used in microfabrication, microfluidic device research, and advanced hydrogel systems requiring controlled permeability and flexibility.
Network Characteristics
- Higher molecular weight than lower PEGDA grades
- Can support lower crosslink density networks
- Often used for softer and more elastic hydrogels
- Compatible with aqueous and hydrophilic systems
Final hydrogel properties depend on polymer concentration, photoinitiator system, curing conditions, additives, and formulation composition.
Preparation Tips
- Prepare solutions using clean laboratory equipment
- Optimize polymer concentration to control gel mechanics
- Adjust curing conditions to tune crosslink density
- Perform formulation trials when developing new hydrogel systems
Handling & Storage
- Store in a cool, dry environment
- Keep container tightly sealed when not in use
- Avoid prolonged exposure to moisture and light
- Follow standard laboratory chemical handling procedures
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FAQ
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1. What is PEGDA 35K used for?
PEGDA 35K is commonly used in hydrogel formation, biomaterials research, drug delivery systems, photopolymer synthesis, and polymer network development.
2. What does PEGDA stand for?
PEGDA stands for poly(ethylene glycol) diacrylate, a PEG-based macromer containing terminal acrylate functional groups.
3. Why use high molecular weight PEGDA?
Higher molecular weight PEGDA grades such as PEGDA 35K can support softer, more flexible hydrogels with lower crosslink density and increased swelling capacity.
4. How are PEGDA hydrogels formed?
PEGDA hydrogels are typically formed through free-radical polymerization using thermal or photoinitiated crosslinking systems.
5. What research fields commonly use PEGDA 35K?
PEGDA 35K is widely used in biomaterials science, tissue engineering, drug delivery, microfluidics, hydrogel development, and photopolymer research.
Safety & Documentation
Follow standard laboratory safety procedures when handling PEGDA materials. Refer to the product Safety Data Sheet (SDS) for complete handling, storage, and hazard information.
