Poly(L-lactide), IV 0.6 dL/g, Ester terminated, Powder

Product Number:

CAS #

CAS # Product #

50317

26161-42-2

Size

Price

$245.00

Quantity

Bulk Request

Request a Bulk Quote

Product Specifications

Spec-50317.pdf

Linear Formula

(C3H4O2)n

Appearance

White to off-white to light tan powder

Biodegradation Time

> 3 years

Molecular Weight

Synonyms

Viscosity

~0.6 dL/g

Glass Transition Temperature (Tg)

60-65°C

Soluble In

Chloroform, dichloromethane (DCM)

Melting Point

~ 173-178°C

Safety Data Sheet (SDS)

No SDS

Handling

Gloves & fume hood

Storage

Protect from moisture. Store at -20°C.

Hazards

Harmless - use normal precautions; Hygroscopic

Hazard Code

N/A

Related Documents

1. Cho YS, Gwak S-J, Cho Y-S. Fabrication of Polycaprolactone/Nano Hydroxyapatite (PCL/nHA) 3D Scaffold with Enhanced In Vitro Cell Response via Design for Additive Manufacturing (DfAM). Polymers. 2021; 13(9):1394.

2.Seyedsalehi, A., Daneshmandi, L., Barajaa, M. et al. Fabrication and characterization of mechanically competent 3D printed polycaprolactone-reduced graphene oxide scaffolds. Sci Rep 10, 22210 (2020).

3. Yong Sang Cho, Meiling Quan, Nae-Un Kang, Hun-Jin Jeong, Myoung Wha Hong, Young Yul Kim, Young-Sam Cho, Strategy for enhancing mechanical properties and bone regeneration of 3D polycaprolactone kagome scaffold: Nano hydroxyapatite composite and its exposure, European Polymer Journal, Volume 134,2020, 109814, ISSN 0014-3057

4. Cho, Y. S., Quan, M., Lee, S.-H., Hong, M. W., Kim, Y. Y., & Cho, Y.-S. (2019). Assessment of osteogenesis for 3D-printed polycaprolactone/hydroxyapatite composite scaffold with enhanced exposure of hydroxyapatite using rat calvarial defect model. Composites Science and Technology, 107844. doi:10.1016/j.compscitech.2019.107844

5. Ho, C.-C., Fang, H.-Y., Wang, B., Huang, T.-H., & Shie, M.-Y. (2017). The effects of Biodentine/polycaprolactone three-dimensional-scaffold with odontogenesis properties on human dental pulp cells. International Endodontic Journal, 51, e291“e300. doi:10.1111/iej.12799

Poly(L - lactide), IV 0.6 dL/g, Ester terminated, Powder - Polysciences

Product Description

High-grade, suitable for biomedical research.
Supplied as micronized powder.

Poly(L-lactide) (PLLA) is a bioresorbable and biodegradable polymer that is highly sought after in the biomedical industry due to its excellent biocompatibility and mechanical properties. It is widely used in the production of medical devices such as sutures, bone plates, tissue scaffolds, and drug delivery systems. PLA is also seeing increased use in tissue engineering applications due to its ability to support cell growth and promote tissue regeneration.

PLA is frequently leveraged in the biomedical industry due to its well-researched biodegradation mechanisms, with the primary biodegradation pathway being via hydrolysis of its ester linkages. The biodegradation rate can vary based on factors such as the specific application, molecular weight, thickness of the final material, pH, the degree of exposure to enzymes, along with other biological factors.

Polysciences offers many PLA/PDLA homopolymer and copolymer products with varying molecular weights that will suit your research needs.