Poly(2-hydroxyethyl methacrylate/methacrylic acid) 90:10 is a hydrophilic methacrylate copolymer that integrates the hydrophilic nature of PHEMA with the ion-exchange capability of methacrylic acid. The methacrylic acid component introduces carboxyl functionality that can support adhesion, pH responsiveness, and controlled-release materials research.
This 90:10 copolymer is useful in biomedical materials research, hydrogel studies, coatings, adhesives, and specialty polymer formulations. It is more readily water-soluble than poly(2-hydroxyethyl methacrylate) in the presence of alkali and aqueous 90% methanol.
Key Properties
- Hydrophilic PHEMA/methacrylic acid copolymer
- Copolymer ratio: 90:10
- Product Number: 08725
- CAS Number: 31693-08-0
- Molecular formula: (C6H10O3.C4H6O2)x
- Size: 10 g
- Appearance: Off-white crystals
- Solubility in NaOH: Pass
- Solubility in methanol solution: Pass
- Storage temperature: 20°C / room temperature
Applications
Biomedical Hydrogel Research
Used in research involving hydrophilic polymer networks, hydrogel materials, soft contact lens materials, and tissue engineering scaffold studies.
Controlled-Release Materials
Useful in pH-responsive controlled-release research where methacrylic acid functionality can influence swelling, ionization, and release behavior.
Coatings
May be used in coating studies where hydrophilicity, adhesion, and pH-responsive polymer behavior are important.
Adhesives
Suitable for specialty adhesive research where the copolymer’s hydrophilic character and carboxyl functionality may support improved bonding interactions.
Polymer Formulation Studies
Applicable to formulation work involving PHEMA-based copolymers, methacrylic acid functionality, aqueous or alkaline processing conditions, and ion-responsive materials.
Solubility & Compatibility
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Solubility: Specified to pass solubility testing in NaOH and methanol solution
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Polymer type: Hydrophilic methacrylate copolymer
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Functional character: Combines hydroxyethyl methacrylate units with methacrylic acid carboxyl functionality
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pH responsiveness: Methacrylic acid groups may influence ionization, swelling, adhesion, and controlled-release behavior
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Compatibility: Performance depends on pH, solvent system, polymer concentration, neutralization state, additives, and processing conditions
Final material behavior should be evaluated under the intended formulation, processing, and application conditions.
Preparation Tips
- Confirm compatibility with the intended solvent system, pH range, buffer, substrate, or polymer formulation before scale-up.
- When working in aqueous or alkaline systems, add gradually under agitation to support uniform dispersion or dissolution.
- Evaluate pH, ionic strength, concentration, and neutralization conditions, as these can affect solubility, swelling, adhesion, and viscosity behavior.
- For coating, adhesive, or hydrogel studies, test film formation, adhesion, swelling, and mechanical properties under target conditions.
- Document solvent, concentration, pH, mixing order, temperature, and processing conditions for reproducible results.
Handling & Storage
- Exercise normal care when handling this material.
- Store at 20°C / room temperature.
- Keep container tightly closed when not in use.
- Protect from contamination and unnecessary environmental exposure.
- Use standard laboratory handling practices.
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Frequently Asked Questions
1. What is Poly(2-hydroxyethyl methacrylate/methacrylic acid) 90:10 used for?
It is used in research involving hydrogels, pH-responsive materials, controlled-release systems, coatings, adhesives, and specialty polymer formulations.
2. What does the 90:10 ratio mean?
The 90:10 ratio indicates a copolymer composition based on 2-hydroxyethyl methacrylate and methacrylic acid units.
3. Is this product soluble in water?
The product specification lists passing solubility in NaOH and methanol solution. The product description notes improved water solubility in the presence of alkali and aqueous 90% methanol.
4. Why is methacrylic acid included in the copolymer?
Methacrylic acid introduces carboxyl functionality that can support ion-exchange behavior, pH responsiveness, adhesion, and controlled-release materials research.
5. Is this product suitable for biomedical or clinical use?
This product is useful for biomedical materials research. Suitability for any medical, clinical, diagnostic, implantable, or regulated use must be independently validated for the intended application.
6. How should this product be stored?
Store at 20°C / room temperature, keep the container tightly closed when not in use, and follow standard laboratory handling practices.
Safety & Documentation
This product is listed as harmless under normal precautions. Exercise normal care when handling this material and refer to the Safety Data Sheet (SDS), product specification, and Certificate of Analysis for safety, handling, and lot-specific guidance.
