Polyethylene Glycol (PEG) 1450, Pharma Grade is a water-soluble, nonionic polyether polymer widely used in pharmaceutical, biotechnology, personal care, coating, and industrial formulation applications. PEG 1450 combines excellent water compatibility with lubricity, humectancy, and formulation versatility, making it useful across a broad range of research and manufacturing environments.
Synonyms and related names: Polyethylene glycol 1450, PEG 1450, macrogol 1450, poly(ethylene glycol).
Polyethylene glycol and poly(ethylene oxide) are chemically identical polymers that differ primarily by molecular weight nomenclature. PEG polymers are hydroxyl-terminated at both ends and are valued for their compatibility with aqueous systems, formulation flexibility, and ease of incorporation into a variety of products.
PEG 1450 is commonly used in pharmaceutical formulations, coatings, excipient development, personal care products, and laboratory applications where water solubility, lubrication, or moisture-retention properties are desired.
Key Properties
- Pharma grade polyethylene glycol
- Average molecular weight approximately 1450
- Water-soluble, nonionic polymer
- Hydroxyl-terminated polyether structure
- Provides lubricity and humectant functionality
- Suitable for formulation and processing applications
Applications
Pharmaceutical Formulations
PEG 1450 is widely used as an excipient, formulation aid, and processing material in pharmaceutical research and manufacturing applications.
Coatings & Surface Treatments
The polymer may be incorporated into coating systems where slip, moisture management, or formulation performance are important considerations.
Personal Care & Cosmetic Formulations
Polyethylene glycol polymers are commonly utilized in personal care and cosmetic formulations due to their water compatibility and formulation versatility.
Biotechnology & Laboratory Research
Researchers use PEG materials in laboratory protocols, formulation development, biomaterials research, and aqueous polymer systems.
Industrial Formulation Development
PEG 1450 may be incorporated into specialty formulations where water solubility, lubrication, or processing characteristics are required.
Material Characteristics
- Nonionic polyether polymer
- Readily soluble in water
- Compatible with many aqueous systems
- Broadly used across research and manufacturing applications
- Chemically equivalent polymer family to poly(ethylene oxide)
Performance depends on concentration, formulation composition, molecular weight distribution, processing conditions, and intended application requirements.
Formulation Considerations
- Select molecular weight appropriate for the intended application
- Evaluate compatibility with formulation ingredients
- Optimize concentration based on performance objectives
- Perform application-specific testing before production use
Handling & Storage
- Store in a cool, dry environment
- Keep container tightly closed when not in use
- Protect from contamination and excessive moisture exposure
- Follow standard laboratory and manufacturing handling procedures
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FAQ
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1. What is PEG 1450?
PEG 1450 is a water-soluble, nonionic polyethylene glycol polymer with an average molecular weight of approximately 1450.
2. What is polyethylene glycol used for?
Polyethylene glycol is commonly used in pharmaceutical formulations, coatings, personal care products, laboratory research, biotechnology applications, and industrial formulations.
3. Are polyethylene glycol and poly(ethylene oxide) the same?
Yes. Polyethylene glycol and poly(ethylene oxide) are chemically identical polymers; the names are generally distinguished by molecular weight conventions.
4. Why is PEG 1450 used in formulations?
PEG 1450 is valued for its water solubility, nonionic nature, lubricity, humectant properties, and formulation versatility.
5. What does pharma grade mean?
Pharma grade indicates the material is intended for pharmaceutical and related formulation applications and is manufactured to applicable quality standards for that product grade.
Safety & Documentation
Follow standard laboratory and manufacturing handling procedures when working with PEG 1450. Refer to the product Safety Data Sheet (SDS) and product documentation for complete handling, storage, and safety information.
