⟡ PEGDGE 1000 / Epoxy Crosslinkers / Hydrogel & Biomaterials Polymers
Poly(ethylene glycol) diglycidyl ether (PEGDGE 1000) is a bifunctional epoxy crosslinker derived from polyethylene glycol. Reactive glycidyl ether groups enable covalent crosslinking with polymers and biomolecules containing nucleophilic functional groups such as amines, hydroxyls, thiols, and carboxyl groups.
The polyethylene glycol backbone provides hydrophilicity, flexibility, and aqueous compatibility, making PEGDGE 1000 widely used in hydrogel formation, polymer modification, biomaterials development, coatings, and flexible epoxy resin systems.
Key Features & Benefits
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Bifunctional epoxy crosslinker: contains two reactive glycidyl ether groups for polymer network formation
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Hydrophilic PEG backbone: supports flexible and water-compatible polymer systems
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Reactive epoxy chemistry: compatible with amines, hydroxyls, thiols, and carboxyl groups
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Flexible polymer network formation: useful for hydrogels and soft material applications
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Widely used in biomaterials: suitable for polymer modification and hydrogel engineering research
Product Details
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Product name: Poly(ethylene glycol) diglycidyl ether (PEGDGE 1000)
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Abbreviation: PEGDGE
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Approximate WPE: ~551
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Approximate repeat units: n ~22
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Chemistry: Polyethylene glycol terminated with glycidyl ether functional groups
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Crosslinking mechanism: Epoxy crosslinking with nucleophilic functional groups
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Applications: Hydrogels, biomaterials, polymer modification, coatings, and epoxy systems
Typical Applications
Hydrogel formation
PEGDGE 1000 is commonly used to form flexible crosslinked hydrophilic polymer networks for hydrogel preparation, biomaterials research, and soft polymer systems.
Biomaterials & tissue engineering
PEG-based epoxy crosslinkers are widely used in biomaterials and tissue engineering applications because of their hydrophilic backbone and compatibility with aqueous systems.
Polymer modification
Reactive epoxide groups enable modification and crosslinking of polymers containing amine, hydroxyl, thiol, and carboxyl functional groups.
Coatings & epoxy systems
PEGDGE 1000 can be incorporated into coating and epoxy resin formulations where flexibility, hydrophilicity, and tunable polymer properties are desired.
Functional Properties
The polyethylene glycol backbone contributes hydrophilicity, flexibility, and water compatibility, while the reactive epoxide groups support efficient crosslinking and polymer network formation.
Compared to lower molecular weight epoxy crosslinkers, PEGDGE 1000 generally supports formation of more flexible and hydrophilic polymer structures, making it useful for hydrogel chemistry and soft biomaterial applications.
Why Use PEGDGE 1000?
PEGDGE 1000 is commonly selected for polymer systems requiring flexible crosslinking chemistry, aqueous compatibility, and tunable polymer network properties. Researchers frequently use PEGDGE materials to tailor hydrogel mechanics and modify polymer structures.
Its combination of epoxy functionality and polyethylene glycol chemistry makes PEGDGE 1000 a versatile crosslinker for biomaterials science, hydrogel engineering, coatings, and polymer research applications.
Handling & Storage
- Store in a cool, dry environment away from excessive heat and moisture.
- Keep containers tightly sealed when not in use.
- Avoid contamination with reactive curing agents during storage.
- Use appropriate laboratory protective equipment during handling.
- Consult the SDS for complete handling and safety information.
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FAQ
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What is PEGDGE 1000 used for?
PEGDGE 1000 is commonly used in hydrogel formation, biomaterials development, polymer modification, coatings, and epoxy resin systems.
What does PEGDGE stand for?
PEGDGE stands for poly(ethylene glycol) diglycidyl ether, a bifunctional epoxy crosslinker derived from polyethylene glycol.
What functional groups react with PEGDGE?
PEGDGE reacts with nucleophilic functional groups including amines, hydroxyl groups, thiols, and carboxyl groups.
Why use PEG-based epoxy crosslinkers?
The polyethylene glycol backbone provides hydrophilicity and flexibility, helping form water-compatible and flexible crosslinked polymer networks.
Where can I buy PEGDGE 1000?
Polysciences supplies PEGDGE 1000 materials for hydrogel development, biomaterials research, polymer modification, and epoxy chemistry applications.
