⟡ PEGDGE 200 / Epoxy Crosslinkers / Hydrogel & Biomaterials Polymers
Poly(ethylene glycol) diglycidyl ether (PEGDGE 200) is a bifunctional epoxy crosslinker derived from polyethylene glycol. Reactive glycidyl ether groups enable covalent crosslinking with polymers and biomolecules containing nucleophilic functional groups such as amines, hydroxyls, and carboxyl groups.
The polyethylene glycol backbone provides hydrophilicity, flexibility, and water compatibility, making PEGDGE 200 widely used in hydrogel formation, biomaterials development, polymer modification, and epoxy resin systems requiring flexible crosslinked polymer networks.
Key Features & Benefits
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Bifunctional epoxy crosslinker: contains two reactive glycidyl ether groups for polymer network formation
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Hydrophilic PEG backbone: supports water compatibility and flexible polymer systems
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Reactive with nucleophilic functional groups: compatible with amines, hydroxyls, thiols, and carboxyl groups
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Useful in hydrogel systems: supports formation of crosslinked hydrophilic polymer networks
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Widely used in biomaterials: suitable for polymer modification and hydrogel research applications
Product Details
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Product name: Poly(ethylene glycol) diglycidyl ether (PEGDGE 200)
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Abbreviation: PEGDGE
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Approximate WPE: ~185
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Approximate repeat units: n ~4
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Chemistry: Polyethylene glycol terminated with glycidyl ether functional groups
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Crosslinking mechanism: Epoxy crosslinking with nucleophilic functional groups
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Applications: Hydrogels, biomaterials, polymer modification, coatings, and epoxy systems
Typical Applications
Hydrogel formation
PEGDGE 200 is commonly used to form crosslinked hydrophilic polymer networks for hydrogel preparation, biomaterials development, and soft polymer systems.
Biomaterials & tissue engineering
PEG-based epoxy crosslinkers are frequently used in biomaterials and tissue engineering research because of their compatibility with aqueous systems and flexible polymer backbone.
Polymer modification
Reactive epoxide groups enable modification and crosslinking of polymers containing amine, hydroxyl, thiol, and carboxyl functional groups.
Epoxy resin systems
PEGDGE 200 can be incorporated into epoxy formulations where hydrophilicity, flexibility, and tunable polymer network properties are desired.
Functional Properties
The polyethylene glycol backbone contributes hydrophilicity, flexibility, and compatibility with aqueous systems, while the reactive epoxide groups enable efficient crosslinking and polymer network formation.
Compared to smaller epoxy crosslinkers, PEGDGE 200 supports formation of more flexible and hydrophilic polymer structures, making it useful for hydrogel chemistry and soft biomaterial applications.
Why Use PEGDGE 200?
PEGDGE 200 is commonly selected for polymer systems requiring hydrophilic crosslinking chemistry, flexible network formation, and compatibility with aqueous environments. Researchers frequently use PEGDGE materials to modify polymer properties and create customized hydrogel systems.
Its combination of epoxy functionality and polyethylene glycol chemistry makes PEGDGE 200 a versatile crosslinker for biomaterials science, hydrogel engineering, coatings, and polymer research applications.
Handling & Storage
- Store in a cool, dry environment away from excessive heat and moisture.
- Keep containers tightly sealed when not in use.
- Avoid contamination with reactive curing agents during storage.
- Use appropriate laboratory protective equipment during handling.
- Consult the SDS for complete handling and safety information.
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FAQ
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What is PEGDGE 200 used for?
PEGDGE 200 is commonly used in hydrogel formation, polymer modification, biomaterials development, and epoxy resin systems.
What does PEGDGE stand for?
PEGDGE stands for poly(ethylene glycol) diglycidyl ether, a bifunctional epoxy crosslinker derived from polyethylene glycol.
What functional groups react with PEGDGE?
PEGDGE reacts with nucleophilic functional groups including amines, hydroxyl groups, thiols, and carboxyl groups.
Why use PEG-based epoxy crosslinkers?
The polyethylene glycol backbone provides hydrophilicity and flexibility, helping form water-compatible and flexible crosslinked polymer networks.
Where can I buy PEGDGE 200?
Polysciences supplies PEGDGE 200 materials for hydrogel development, biomaterials research, polymer modification, and epoxy chemistry applications.
