Poly(N-iso-propylacrylamide)

Product Number:

CAS #

CAS # Product #

21458

25189-55-3

Size

Price

$70.04

Quantity

Bulk Request

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Product Specifications

Spec-21458.pdf

Molecular Weight

~40,000

Safety Data Sheet (SDS)

SDS_21458.pdf

Handling

Exercise normal care

Storage

Store at room temperature

Hazards

Hazard Code

A2g

Related Documents

Nuopponen, M., Ojala, J. & Tenhu, H. Aggregation behaviour of well defined amphiphilic diblock copolymers with poly(N-isopropylacrylamide) and hydrophobic blocks. Polymer 45, 3643“3650 (2004). doi:10.1016/j.polymer.2004.03.083

Zhang, J. & Peppas, N. A. Synthesis and Characterization of pH- and Temperature-Sensitive Poly(methacrylic acid)/Poly( N -isopropylacrylamide) Interpenetrating Polymeric Networks. Macromolecules 33, 102“107 (2000). doi:10.1021/ma991398q

Feil, H., Bae, Y. H., Feijen, J. & Kim, S. W. Effect of comonomer hydrophilicity and ionization on the lower critical solution temperature of N-isopropylacrylamide copolymers. Macromolecules 26, 2496“2500 (1993). doi:10.1021/ma00062a016

Product Description

Poly(N-iso-propylacrylamide) (PNIPAM) is a temperature-responsive polymer that undergoes a phase transition at its lower critical solution temperature (LCST) of ~32 - 40°C. Below the LCST, PNIPAM is hydrophilic and soluble in water, while above it, the polymer becomes hydrophobic and precipitates. This unique behavior makes it highly valuable in stimuli-responsive materials and smart biomedical applications.

Applications:

Biomedical & Drug Delivery: Used in thermoresponsive hydrogels, drug carriers, and tissue engineering scaffolds for controlled release systems.
Smart Coatings: Integrated into responsive coatings that alter surface wettability and adhesion properties with temperature changes.
Bioseparations: Applied in affinity chromatography and cell culture systems to enable temperature-controlled material interactions.