Poly(propylene glycol) (400) dimethacrylate (PPGDMA) is a difunctional polyether macromer containing terminal methacrylate groups. The two polymerizable end groups allow PPGDMA to participate in free-radical polymerization and introduce covalent junctions into crosslinked polymer networks.
Synonyms: PPGDMA; poly(propylene glycol) dimethacrylate; PPG dimethacrylate.
The 400 designation refers to the nominal molecular weight of the poly(propylene glycol) block rather than the molecular weight of the complete methacrylate-functionalized macromer. The PPG segment provides a flexible polyether spacer between the two reactive methacrylate groups, while final network properties depend on PPGDMA concentration, conversion, comonomer composition, and curing conditions.
Key Properties
- Difunctional PPG-based methacrylate macromer
- Two terminal polymerizable methacrylate groups
- Nominal molecular weight of PPG block: 400
- CAS Number: 25852-49-7
- Appearance: colorless to yellow liquid
- Viscosity at 25°C: 27 mPa·s
- Inhibitors: 100 ppm MEHQ and 100 ppm BHT
- Refractive index: 1.452
- Catalog number: 04380
- Available sizes: 250 g and 1 kg
- Storage: 4°C
Applications
Crosslinked Polymer Networks
PPGDMA is used as a difunctional crosslinking macromer in free-radical polymerization. Reaction through both terminal methacrylate groups allows the PPG segment to become incorporated between network junctions.
Methacrylate Resin Research
PPGDMA can be incorporated into multi-monomer methacrylate formulations when a flexible polyether-containing crosslinker is required. Network composition, conversion, crosslink density, and comonomer selection determine the properties of the resulting resin.
Dental Composite Formulation Research
Poly(propylene glycol) dimethacrylate has been studied as a comonomer in experimental dental composite formulations. Its use in research formulations does not by itself establish medical-device or clinical suitability for this grade.
Photopolymerization Research
PPGDMA may be used in photopolymerized methacrylate systems where its two reactive end groups participate in network formation. Cure response depends on photoinitiator chemistry, irradiation conditions, oxygen exposure, formulation composition, and sample geometry.
Polymerization & Formulation Considerations
- The two methacrylate groups can form covalent network junctions during free-radical polymerization
- The 400 designation refers to the PPG block and should not be interpreted as the molecular weight of the complete functionalized macromer
- MEHQ and BHT are present as inhibitors and should be considered when establishing initiation and cure conditions
- Crosslink density depends on PPGDMA concentration, conversion, and the functionality of other formulation components
- Final mechanical, swelling, and solvent-response properties are properties of the polymer network, not intrinsic properties of the uncured macromer
Poly(propylene glycol) (400) dimethacrylate should not be confused with polypropylene glycol 400. PPG 400 is an unfunctionalized polyether polyol, whereas PPGDMA contains polymerizable methacrylate end groups and functions as a reactive component in methacrylate polymerization.
Application Tips
- Account for the 100 ppm MEHQ and 100 ppm BHT inhibitor levels when establishing radical initiation or photopolymerization conditions
- Keep PPGDMA concentration and comonomer ratios consistent when comparing network properties between formulations
- Control oxygen exposure during free-radical curing when surface conversion is important
- Use consistent irradiation wavelength, irradiance, and exposure time in photopolymerization studies
- Measure conversion when comparing cure conditions or formulation changes
Handling & Storage
- Store at 4°C in a cool, well-ventilated location
- Keep the container tightly closed when not in use
- Handle with good laboratory ventilation or in a chemical fume hood
- Wear protective gloves, safety glasses, and suitable protective clothing
- Avoid contact with skin and eyes and avoid breathing vapor or mist
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FAQ
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1. What is PPGDMA?
PPGDMA is poly(propylene glycol) dimethacrylate, a difunctional macromer containing a poly(propylene glycol) segment terminated with two polymerizable methacrylate groups.
2. What does the 400 in Poly(propylene glycol) (400) dimethacrylate mean?
The 400 designation refers to the nominal molecular weight of the PPG block. It is not the molecular weight of the complete methacrylate-functionalized macromer.
3. Is PPGDMA 400 the same as polypropylene glycol 400?
No. Polypropylene glycol 400 is a hydroxyl-terminated polyether, while PPGDMA contains terminal methacrylate groups that can participate in free-radical polymerization. They should not be treated as interchangeable materials.
4. What is the CAS number for Poly(propylene glycol) (400) dimethacrylate?
The CAS number is 25852-49-7.
5. What package sizes are available?
Catalog number 04380 is available in 250 g and 1 kg sizes. For larger quantities, use the bulk-quote option.
Safety & Documentation
Use appropriate laboratory ventilation and personal protective equipment when handling PPGDMA. Avoid skin and eye contact and minimize inhalation exposure to vapor or mist. Refer to the Safety Data Sheet (SDS) for complete hazard, handling, storage, transport, and disposal information.
