Boc-amine PEG thiol, Mp 3000

Boc-Amine PEG Thiol is a heterobifunctional PEG linker featuring a thiol (-SH) group for thiol-maleimide conjugation and a Boc-protected amine for later deprotection and subsequent functionalization. The thiol group facilitates covalent attachment to gold surfaces, quantum dots, and maleimide-functionalized molecules, while the PEG spacer improves solubility and reduces steric hindrance. This dual functionality makes it ideal for stepwise bioengineering and nanomaterial surface modifications.

Applications:
Nanoparticle Functionalization: Enables stable thiol-gold or thiol-maleimide coupling for biosensors and drug carriers.
Bioconjugation Strategies: Allows precise sequential modification of proteins, peptides, and surfaces.
PEGylation for Drug Delivery: Enhances stability and circulation time of therapeutic agents.
Self-Assembled Monolayers (SAMs): Forms robust layers on metal surfaces for biointerfaces.